Literature DB >> 1612745

Cross-reacting serum opsonins in patients with meningococcal disease.

H K Guttormsen1, R Bjerknes, A Naess, V Lehmann, A Halstensen, S Sørnes, C O Solberg.   

Abstract

We have examined the opsonic activity of sera from patients with Neisseria meningitidis (B:15:P1.16) infections against different meningococcal strains, using flow cytometry and luminol-enhanced chemiluminescence. A marked increase in the phagocytosis of ethanol-fixed meningococcal strains of different serogroups, serotypes, and serosubtypes was demonstrated in the presence of convalescence sera compared with acute sera. Convalescence sera also caused a significant increase of leukocyte oxidative metabolism during phagocytosis, as measured by luminol-enhanced chemiluminescence. The sera contained a broad range of opsonins cross-reacting with serogroup A, B, C, W-135, and Y meningococci of different serotypes and serosubtypes, indicating that the cross-reacting opsonins recognized surface epitopes other than those determined by current serotyping schemes.

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Year:  1992        PMID： 1612745      PMCID： PMC257234          DOI： 10.1128/iai.60.7.2777-2783.1992

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  21 in total

Review 1.  Serotype antigens of Neisseria meningitidis and a proposed scheme for designation of serotypes.

Authors:  C E Frasch; W D Zollinger; J T Poolman
Journal:  Rev Infect Dis       Date:  1985 Jul-Aug

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Authors:  M L Lepow; J Beeler; M Randolph; J S Samuelson; W A Hankins
Journal:  J Infect Dis       Date:  1986-12       Impact factor: 5.226

3.  Spirometric abnormalities in young smokers correlate with increased chemiluminescence responses of activated blood phagocytes.

Authors:  G A Richards; A J Theron; C A Van der Merwe; R Anderson
Journal:  Am Rev Respir Dis       Date:  1989-01

4.  Standardization of a chemiluminescence method for the measurement of meningococcal opsonins using ethanol fixed meningococci.

Authors:  A Halstensen; B Haneberg
Journal:  Acta Pathol Microbiol Immunol Scand C       Date:  1987-08

5.  Serum antibodies to cross-reactive Neisseria outer membrane antigens in healthy persons and patients with meningococcal disease.

Authors:  J A Maeland; E Wedege
Journal:  APMIS       Date:  1989-09       Impact factor: 3.205

6.  Serum opsonins to serogroup B meningococci in meningococcal disease.

Authors:  A Halstensen; H Sjursen; S E Vollset; L O Frøholm; A Naess; R Matre; C O Solberg
Journal:  Scand J Infect Dis       Date:  1989

7.  Opsonisation and phagocytosis of group B meningococci by polymorphonuclear leucocytes: comparison of sulphonamide sensitive and resistant strains.

Authors:  K N Ward; A Fleer; J Verhoef; D M Jones
Journal:  J Clin Pathol       Date:  1987-04       Impact factor: 3.411

8.  Killing of Neisseria meningitidis by human neutrophils: implications for normal and complement-deficient individuals.

Authors:  S C Ross; P J Rosenthal; H M Berberich; P Densen
Journal:  J Infect Dis       Date:  1987-06       Impact factor: 5.226

9.  Human monoclonal antibody with protective activity for Escherichia coli K1 and Neisseria meningitidis group B infections.

Authors:  H V Raff; D Devereux; W Shuford; D Abbott-Brown; G Maloney
Journal:  J Infect Dis       Date:  1988-01       Impact factor: 5.226

10.  The interaction in vitro between group B meningococci and rabbit polymorphonuclear leukocytes. Demonstration of type specific opsonins and bactericidins.

Authors:  R B Roberts
Journal:  J Exp Med       Date:  1967-11-01       Impact factor: 14.307
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  7 in total

1.  Human opsonins induced during meningococcal disease recognize outer membrane proteins PorA and PorB.

Authors:  A K Lehmann; A Halstensen; I S Aaberge; J Holst; T E Michaelsen; S Sornes; L M Wetzler; H Guttormsen
Journal:  Infect Immun       Date:  1999-05       Impact factor: 3.441

2.  Immune response induction and new effector mechanisms possibly involved in protection conferred by the Cuban anti-meningococcal BC vaccine.

Authors:  O Pérez; M Lastre; J Lapinet; G Bracho; M Díaz; C Zayas; C Taboada; G Sierra
Journal:  Infect Immun       Date:  2001-07       Impact factor: 3.441

3.  Functional opsonic activity of human serum antibodies to inner core lipopolysaccharide (galE) of serogroup B meningococci measured by flow cytometry.

Authors:  J S Plested; B L Ferry; P A Coull; K Makepeace; A K Lehmann; F G MacKinnon; H G Griffiths; M A Herbert; J C Richards; E R Moxon
Journal:  Infect Immun       Date:  2001-05       Impact factor: 3.441

4.  Human opsonins induced during meningococcal disease recognize transferrin binding protein complexes.

Authors:  A K Lehmann; A R Gorringe; K M Reddin; K West; I Smith; A Halstensen
Journal:  Infect Immun       Date:  1999-12       Impact factor: 3.441

5.  Neisserial porins inhibit human neutrophil actin polymerization, degranulation, opsonin receptor expression, and phagocytosis but prime the neutrophils to increase their oxidative burst.

Authors:  R Bjerknes; H K Guttormsen; C O Solberg; L M Wetzler
Journal:  Infect Immun       Date:  1995-01       Impact factor: 3.441

6.  Humoral immune response to the class 3 outer membrane protein during the course of meningococcal disease.

Authors:  H K Guttormsen; L M Wetzler; A Naess
Journal:  Infect Immun       Date:  1993-11       Impact factor: 3.441

7.  Development, characterization, and biological properties of meningococcal immunotype L3,7,(8),9-specific monoclonal antibodies.

Authors:  A F Verheul; A J Kuipers; A K Braat; H A Dekker; C C Peeters; H Snippe; J T Poolman
Journal:  Clin Diagn Lab Immunol       Date:  1994-11
  7 in total

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