Literature DB >> 1612600

Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors (FPRH1, FPRH2) to chromosome 19.

L Bao1, N P Gerard, R L Eddy, T B Shows, C Gerard.   

Abstract

The genes encoding receptors for the chemotactic ligands C5a (C5AR) and FMLP (FPR) were mapped using a panel of somatic cell hybrids to chromosome 19. Because the hybridization pattern on Southern analysis suggested an intron structure or related genes in the case of FPR, genomic clones were characterized. Two structural homologues of the FMLP receptor, clones 81 (FPRH1) and 82 (FPRH2), were identified, which similarly map to chromosome 19. The structural homologues do not recognize the ligand FMLP, but are likely chemotactic receptors.

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Year:  1992        PMID： 1612600     DOI： 10.1016/0888-7543(92)90265-t

Source DB:  PubMed          Journal:  Genomics        ISSN： 0888-7543            Impact factor:   5.736


  41 in total

Review 1.  New development in studies of formyl-peptide receptors: critical roles in host defense.

Authors:  Liangzhu Li; Keqiang Chen; Yi Xiang; Teizo Yoshimura; Shaobo Su; Jianwei Zhu; Xiu-wu Bian; Ji Ming Wang
Journal:  J Leukoc Biol       Date:  2015-12-23       Impact factor: 4.962

2.  Computational structure-activity relationship analysis of small-molecule agonists for human formyl peptide receptors.

Authors:  Andrei I Khlebnikov; Igor A Schepetkin; Mark T Quinn
Journal:  Eur J Med Chem       Date:  2010-09-15       Impact factor: 6.514

Review 3.  Expression and signaling of formyl-peptide receptors in the brain.

Authors:  Fabio Cattaneo; Germano Guerra; Rosario Ammendola
Journal:  Neurochem Res       Date:  2010-11-02       Impact factor: 3.996

4.  Duplex high-throughput flow cytometry screen identifies two novel formylpeptide receptor family probes.

Authors:  Susan M Young; Cristian M Bologa; Dan Fara; Bj K Bryant; Juan Jacob Strouse; Jeffrey B Arterburn; Richard D Ye; Tudor I Oprea; Eric R Prossnitz; Larry A Sklar; Bruce S Edwards
Journal:  Cytometry A       Date:  2009-03       Impact factor: 4.355

Review 5.  Novel anti-inflammatory--pro-resolving mediators and their receptors.

Authors:  Charles N Serhan; Sriram Krishnamoorthy; Antonio Recchiuti; Nan Chiang
Journal:  Curr Top Med Chem       Date:  2011       Impact factor: 3.295

6.  Peptide surfactants for cell-free production of functional G protein-coupled receptors.

Authors:  Xiaoqiang Wang; Karolina Corin; Philipp Baaske; Christoph J Wienken; Moran Jerabek-Willemsen; Stefan Duhr; Dieter Braun; Shuguang Zhang
Journal:  Proc Natl Acad Sci U S A       Date:  2011-05-11       Impact factor: 11.205

Review 7.  Enemy attraction: bacterial agonists for leukocyte chemotaxis receptors.

Authors:  Dominik Alexander Bloes; Dorothee Kretschmer; Andreas Peschel
Journal:  Nat Rev Microbiol       Date:  2014-12-15       Impact factor: 60.633

8.  A proinflammatory peptide from Helicobacter pylori activates monocytes to induce lymphocyte dysfunction and apoptosis.

Authors:  J Bylund; T Christophe; T Cristophe; F Boulay; A Romero; K Hellstrand; C Dahlgren
Journal:  J Clin Invest       Date:  2001-10       Impact factor: 14.808

9.  Identification of novel small-molecule agonists for human formyl peptide receptors and pharmacophore models of their recognition.

Authors:  Liliya N Kirpotina; Andrei I Khlebnikov; Igor A Schepetkin; Richard D Ye; Marie-Josèphe Rabiet; Mark A Jutila; Mark T Quinn
Journal:  Mol Pharmacol       Date:  2009-11-10       Impact factor: 4.436

10.  Molecular evolution of the N-formyl peptide and C5a receptors in non-human primates.

Authors:  V Alvarez; E Coto; F Setién; S González-Roces; C López-Larrea
Journal:  Immunogenetics       Date:  1996       Impact factor: 2.846
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