Literature DB >> 16125097

Calcium liberates PNAs from endosomes.

David R Corey1.   

Abstract

Many peptides are reported to enhance cellular uptake of peptide nucleic acids and other macromolecules. Cellular uptake, however, is not synonymous with cellular activity. In this issue of Chemistry and Biology, Nielsen and colleagues examine the traffic of PNAs and investigate protocols for improving recognition of target mRNA inside cells.

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Year:  2005        PMID: 16125097     DOI: 10.1016/j.chembiol.2005.08.003

Source DB:  PubMed          Journal:  Chem Biol        ISSN: 1074-5521


  1 in total

1.  Hydroxyproline-based DNA mimics provide an efficient gene silencing in vitro and in vivo.

Authors:  Vladimir A Efimov; Klara R Birikh; Dmitri B Staroverov; Sergei A Lukyanov; Maria B Tereshina; Andrey G Zaraisky; Oksana G Chakhmakhcheva
Journal:  Nucleic Acids Res       Date:  2006-05-02       Impact factor: 16.971

  1 in total

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