Literature DB >> 16125067

Use of corporate Six Sigma performance-improvement strategies to reduce incidence of catheter-related bloodstream infections in a surgical ICU.

Heidi L Frankel1, William B Crede, Jeffrey E Topal, Sarah A Roumanis, Marie W Devlin, Andrea B Foley.   

Abstract

BACKGROUND: Corporate performance-improvement methodologies can outperform traditional ones in addressing ICU-based adverse events. My colleagues and I used Six Sigma methodology to address our catheter-related bloodstream infection (CR-BSI) rate, which considerably exceeded the nationally established median over a 9-year period. We hypothesized that use of Six Sigma methodology would result in a substantial and sustainable decrease in our CR-BSI rate. STUDY
DESIGN: All patients were directly cared for by a geographically localized surgical ICU team in an academic tertiary referral center. CR-BSIs were identified by infection control staff using CDC definitions. Personnel trained in Six Sigma techniques facilitated performance-improvement efforts. Interventions included barrier precaution kits, new policies for catheter changes over guide wires, adoption of a new site-preparation antiseptic, direct attending supervision of catheter insertions, video training for housestaff, and increased frequency of dressing changes. After additional data analysis, chlorhexidine-silver catheters were used selectively in high-risk patients. The impact of interventions was assessed by monitoring the number of catheters placed between CR-BSIs.
RESULTS: Before the intervention period, 27 catheters were placed, on average, between individual CR-BSIs, a CR-BSI rate of 11 per 1,000 catheter days. After all operations were implemented, 175 catheters were placed between line infections, and average CR-BSI rate of 1.7/1,000 catheter days, a 650% improvement (p < 0.0001). Compared with historic controls, adoption of chlorhexidine-silver catheters in high-risk patients had a considerable impact (50% reduction; p < 0.05).
CONCLUSIONS: This represents the first successful application of Six Sigma corporate performance-improvement method impacting purely clinical outcomes. CR-BSI reduction was highly substantial and sustained after other traditional strategies had failed.

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Year:  2005        PMID: 16125067     DOI: 10.1016/j.jamcollsurg.2005.04.027

Source DB:  PubMed          Journal:  J Am Coll Surg        ISSN: 1072-7515            Impact factor:   6.113


  15 in total

1.  Intravascular catheter-related bloodstream infection.

Authors:  Harshal Shah; Wendelyn Bosch; Kristine M Thompson; Walter C Hellinger
Journal:  Neurohospitalist       Date:  2013-07

2.  Effects of blood glucose transcription mismatches on a computer-based intensive insulin therapy protocol.

Authors:  Thomas R Campion; Addison K May; Lemuel R Waitman; Asli Ozdas; Cynthia S Gadd
Journal:  Intensive Care Med       Date:  2010-03-30       Impact factor: 17.440

3.  Summary of recommendations: Guidelines for the Prevention of Intravascular Catheter-related Infections.

Authors:  Naomi P O'Grady; Mary Alexander; Lillian A Burns; E Patchen Dellinger; Jeffrey Garland; Stephen O Heard; Pamela A Lipsett; Henry Masur; Leonard A Mermel; Michele L Pearson; Issam I Raad; Adrienne G Randolph; Mark E Rupp; Sanjay Saint
Journal:  Clin Infect Dis       Date:  2011-05       Impact factor: 9.079

4.  Guidelines for the prevention of intravascular catheter-related infections.

Authors:  Naomi P O'Grady; Mary Alexander; Lillian A Burns; E Patchen Dellinger; Jeffrey Garland; Stephen O Heard; Pamela A Lipsett; Henry Masur; Leonard A Mermel; Michele L Pearson; Issam I Raad; Adrienne G Randolph; Mark E Rupp; Sanjay Saint
Journal:  Clin Infect Dis       Date:  2011-04-01       Impact factor: 9.079

5.  Can we apply the process improvement tool Six Sigma to enhance outcomes in hepatopancreatobiliary surgery?

Authors:  Parul J Shukla; Savio G Barreto
Journal:  HPB (Oxford)       Date:  2009-03       Impact factor: 3.647

Review 6.  Prevention of central line-associated bloodstream infections through quality improvement interventions: a systematic review and meta-analysis.

Authors:  Koen Blot; Jochen Bergs; Dirk Vogelaers; Stijn Blot; Dominique Vandijck
Journal:  Clin Infect Dis       Date:  2014-04-09       Impact factor: 9.079

7.  What is new for the prevention of catheter-related bloodstream infections?

Authors:  Leonardo Lorente
Journal:  Ann Transl Med       Date:  2016-03

Review 8.  Economic Evaluation of Quality Improvement Interventions for Bloodstream Infections Related to Central Catheters: A Systematic Review.

Authors:  Teryl K Nuckols; Emmett Keeler; Sally C Morton; Laura Anderson; Brian Doyle; Marika Booth; Roberta Shanman; Jonathan Grein; Paul Shekelle
Journal:  JAMA Intern Med       Date:  2016-12-01       Impact factor: 21.873

9.  The 'pit-crew' model for improving door-to-needle times in endovascular stroke therapy: a Six-Sigma project.

Authors:  Ansaar T Rai; Matthew S Smith; SoHyun Boo; Abdul R Tarabishy; Gerald R Hobbs; Jeffrey S Carpenter
Journal:  J Neurointerv Surg       Date:  2016-01-11       Impact factor: 5.836

10.  A critical review of the research literature on Six Sigma, Lean and StuderGroup's Hardwiring Excellence in the United States: the need to demonstrate and communicate the effectiveness of transformation strategies in healthcare.

Authors:  Joshua R Vest; Larry D Gamm
Journal:  Implement Sci       Date:  2009-07-01       Impact factor: 7.327

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