| Literature DB >> 16124786 |
Gerhard Lang1, John W Blunt, Nicholas J Cummings, Anthony L J Cole, Murray H G Munro.
Abstract
The entomopathogenic fungus Hirsutella sp., isolated from an infected spider, was found to produce the new cyclotetrapeptide hirsutide (1), cyclo-(L-NMe-Phe-L-Phe-L-NMe-Phe-L-Val), along with the known cytochalasin Q (2), using a cytotoxicity-guided isolation procedure. The structure of 1 was elucidated using one- and two-dimensional NMR experiments, mass spectrometry, and Marfey's method for analyzing the configuration of the amino acids.Entities:
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Year: 2005 PMID： 16124786 DOI： 10.1021/np0501536
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050