| Literature DB >> 16124781 |
Shu-Hua Qi1, Si Zhang, Xiang Li, Qing-Xin Li.
Abstract
A new sesquiterpene alkaloid, 6-(9'-purine-6',8'-diolyl)-2beta-suberosanone (1), together with three known sesquiterpenes, suberosenol A (2), subergorgic acid (3), and subergorgiol (4), was isolated from the EtOH/CH2Cl2 extracts of the South China Sea gorgonian Subergorgia suberosa. The structure of 1 was determined through spectroscopic methods. Compound 1 showed moderate cytotoxicity against the human breast carcinoma MDA-MB-231 cell line with an IC50 of 8.87 microg/mL.Entities:
Mesh：
Substances：
Year: 2005 PMID： 16124781 DOI： 10.1021/np050105l
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050