| Literature DB >> 16124409 |
D T Huong1, D V Luong, T T P Thao, T V Sung.
Abstract
A new flavone named miliufavol [8-(2-hydroxybenzyl)-5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,7-dimethoxy-4H-chromen-4-one or 8-C-(o)-hydroxybenzylpachypodol] from Miliusa balansae (Annonaceae) was isolated and structurally elucidated by spectroscopic means besides four known flavones: ombuine, chrysosplenol B, pachypodol and chrysosplenol C. These flavonoids exhibited interesting cytotoxic activity against three human cell lines (KB, Hep-G2, RD) with IC50 values < 5 microg/ml.Entities:
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Year: 2005 PMID: 16124409
Source DB: PubMed Journal: Pharmazie ISSN: 0031-7144 Impact factor: 1.267