Literature DB >> 16123871

[Prevalence of latent and manifest hyperthyroidism in an iodine-deficient area: non-selected patient population admitted for CT studies with iodine-containing contrast agents].

T Saam1, T Hess, C Kasperk, G W Kauffmann, M Düx.   

Abstract

PURPOSE: To evaluate the prevalence of latent and manifest hyperthyroidism in a non-selected group of patients admitted for contrast enhanced CT studies blood samples were tested for the levels of thyroid-stimulating hormone (TSH).
MATERIAL AND METHODS: TSH blood levels were obtained in 548 consecutive patients who were scheduled for contrast-enhanced (Iopromide; 300 mg iodine/ml) CT scanning. In case of TSH levels < 0.4 mU/l, blood samples were also tested for triiodothyronine (T3) and tetraiodothyronine (T4) blood levels, and treatment with Irenat (sodium perchlorate) was commenced before scanning. In case of TSH levels < 0.1 mU/l, CT scanning was not performed but further evaluation of the thyroid function was initiated.
RESULTS: TSH blood levels ranged from 0.4 to 7.5 mU/l in 512 patients, and 36 patients (6.6%) had TSH blood levels < 0.4 mU/l and 9 patients blood levels < 0.1 mU/l, with 32 of those patients (5.8%) having regular T3 and T4 blood levels consistent with latent hyperthyroidism. In 4 patients (0.8%), T3 or T4 blood levels were increased consistent with manifest hyperthyroidism.
CONCLUSION: In South Germany, the prevalence of latent or manifest hyperthyroidism in a non-selected patient group is high. Therefore TSH blood levels should be obtained prior to contrast-enhanced CT studies.

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Year:  2005        PMID: 16123871     DOI: 10.1055/s-2005-858237

Source DB:  PubMed          Journal:  Rofo        ISSN: 1438-9010


  2 in total

Review 1.  [Complications due to contrast agent administration: what has been confirmed in prevention?].

Authors:  E Schönenberger; M Mühler; M Dewey
Journal:  Internist (Berl)       Date:  2010-12       Impact factor: 0.743

2.  [Prophylaxis and treatment of side effects due to iodinated contrast media relevant to radiological practice].

Authors:  C Becker
Journal:  Radiologe       Date:  2007-09       Impact factor: 0.635

  2 in total

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