Literature DB >> 16123805

TGF-beta, neuronal stem cells and glioblastoma.

Nady Golestaneh1, Bibhuti Mishra.   

Abstract

Transforming growth factor beta (TGF-beta) signaling leads to a number of biological end points involving cell growth, differentiation, and morphogenesis. Typically, the cellular effect accompanies an induction of mesodermal cell fate and inhibition of neural cell differentiation. However, during pathological conditions, these defined effects of TGF-beta can be reversed; for example, the growth-inhibitory effect is replaced with its tumor promoting ability. A multitude of factors and cross-signaling pathways have been reported to be involved in modulating the dual effects of TGF-beta. In this review, we focus on the potential role of TGF-beta signal transduction during development of neural progenitor cells and its relation to glioblastoma development from neural stem cells.

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Year:  2005        PMID： 16123805     DOI： 10.1038/sj.onc.1208925

Source DB:  PubMed          Journal:  Oncogene        ISSN： 0950-9232            Impact factor:   9.867


  31 in total

Review 1.  Moving from the laboratory bench to patients' bedside: considerations for effective therapy with stem cells.

Authors:  Lauren S Sherman; Jessian Munoz; Shyam A Patel; Meneka A Dave; Ilani Paige; Pranela Rameshwar
Journal:  Clin Transl Sci       Date:  2011-10       Impact factor: 4.689

2.  TGFβ-Responsive HMOX1 Expression Is Associated with Stemness and Invasion in Glioblastoma Multiforme.

Authors:  Dhiman Ghosh; Ilya V Ulasov; LiPing Chen; Lualhati E Harkins; Karolina Wallenborg; Parvinder Hothi; Steven Rostad; Leroy Hood; Charles S Cobbs
Journal:  Stem Cells       Date:  2016-07-04       Impact factor: 6.277

3.  A Phase II randomized study of galunisertib monotherapy or galunisertib plus lomustine compared with lomustine monotherapy in patients with recurrent glioblastoma.

Authors:  Alba A Brandes; Antoine F Carpentier; Santosh Kesari; Juan M Sepulveda-Sanchez; Helen R Wheeler; Olivier Chinot; Lawrence Cher; Joachim P Steinbach; David Capper; Pol Specenier; Jordi Rodon; Ann Cleverly; Claire Smith; Ivelina Gueorguieva; Colin Miles; Susan C Guba; Durisala Desaiah; Michael M Lahn; Wolfgang Wick
Journal:  Neuro Oncol       Date:  2016-02-21       Impact factor: 12.300

4.  Androgen receptor signaling regulates growth of glioblastoma multiforme in men.

Authors:  Xiaoming Yu; Yuhua Jiang; Wei Wei; Ping Cong; Yinlu Ding; Lei Xiang; Kang Wu
Journal:  Tumour Biol       Date:  2014-10-15

5.  Human stem/progenitor cells from bone marrow enhance glial differentiation of rat neural stem cells: a role for transforming growth factor β and Notch signaling.

Authors:  Andrew P Robinson; Jessica E Foraker; Joni Ylostalo; Darwin J Prockop
Journal:  Stem Cells Dev       Date:  2010-09-14       Impact factor: 3.272

6.  A Cell-Surface Membrane Protein Signature for Glioblastoma.

Authors:  Dhimankrishna Ghosh; Cory C Funk; Juan Caballero; Nameeta Shah; Katherine Rouleau; John C Earls; Liliana Soroceanu; Greg Foltz; Charles S Cobbs; Nathan D Price; Leroy Hood
Journal:  Cell Syst       Date:  2017-03-29       Impact factor: 10.304

7.  Growth factors from tumor microenvironment possibly promote the proliferation of glioblastoma-derived stem-like cells in vitro.

Authors:  JingJing Guo; Rui Niu; Wenhui Huang; Mengliang Zhou; Jixing Shi; Luyong Zhang; Hong Liao
Journal:  Pathol Oncol Res       Date:  2012-07-28       Impact factor: 3.201

8.  Expression of Notch and Wnt pathway components and activation of Notch signaling in medulloblastomas from heterozygous patched mice.

Authors:  Gabriel D Dakubo; Chantal J Mazerolle; Valerie A Wallace
Journal:  J Neurooncol       Date:  2006-04-06       Impact factor: 4.130

9.  Suppression of the proliferation of human U-87 MG glioblastoma cells by new antagonists of growth hormone-releasing hormone in vivo and in vitro.

Authors:  Miklos Jaszberenyi; Andrew V Schally; Norman L Block; Marta Zarandi; Ren-Zhi Cai; Irving Vidaurre; Luca Szalontay; Arumugam R Jayakumar; Ferenc G Rick
Journal:  Target Oncol       Date:  2013-02-01       Impact factor: 4.493

10.  Glioblastoma Multiforme Oncogenomics and Signaling Pathways.

Authors:  Okezie O Kanu; Betsy Hughes; Chunhui Di; Ningjing Lin; Jinrong Fu; Darell D Bigner; Hai Yan; Cory Adamson
Journal:  Clin Med Oncol       Date:  2009-04-08
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