| Literature DB >> 16123683 |
Silvia M Montano1, Jose L Sanchez, Alberto Laguna-Torres, Paloma Cuchi, Maria M Avila, Mercedes Weissenbacher, Margarita Serra, Jose Viñoles, Jose C Russi, Nicolas Aguayo, Adolfo H Galeano, Alberto Gianella, Ronald Andrade, Anabella Arredondo, Eugenio Ramirez, Maria E Acosta, Aracely Alava, Orlando Montoya, Angel Guevara, Hugo Manrique, Jorge L Sanchez, Javier R Lama, Fernando de la Hoz, Gloria I Sanchez, Claudia Ayala, Maria E Pacheco, Gladys Carrion, Gloria Chauca, Juan J Perez, Monica Negrete, Kevin L Russell, Christian T Bautista, James G Olson, Douglas M Watts, Deborah L Birx, Jean K Carr.
Abstract
HIV cross-sectional studies were conducted among high-risk populations in 9 countries of South America. Enzyme-linked immunosorbent assay screening and Western blot confirmatory testing were performed, and env heteroduplex mobility assay genotyping and DNA sequencing were performed on a subset of HIV-positive subjects. HIV prevalences were highest among men who have sex with men (MSM; 2.0%-27.8%) and were found to be associated with multiple partners, noninjection drug use (non-IDU), and sexually transmitted infections (STIs). By comparison, much lower prevalences were noted among female commercial sex workers (FCSWs; 0%-6.3%) and were associated mainly with a prior IDU and STI history. Env subtype B predominated among MSM throughout the region (more than 90% of strains), whereas env subtype F predominated among FCSWs in Argentina and male commercial sex workers in Uruguay (more than 50% of strains). A renewed effort in controlling STIs, especially among MSM groups, could significantly lessen the impact of the HIV epidemic in South America.Entities:
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Year: 2005 PMID： 16123683 DOI： 10.1097/01.qai.0000159667.72584.8b
Source DB: PubMed Journal: J Acquir Immune Defic Syndr ISSN： 1525-4135 Impact factor: 3.731