Literature DB >> 16122497

Symptoms plus family history trump size in thoracic aortic aneurysm.

John A Elefteriades1, Maryann Tranquilli, Umer Darr, James Cardon, B-Q Zhu, Peter Barrett.   

Abstract

A 43-year-old woman presented with chest pain of unclear cause. The patient's mother and brother had suffered aortic dissection. Echocardiography had shown mild dilatation of the ascending aorta at 4.0 cm. Echocardiogram and magnetic resonance imaging were negative for dissection. The patient was taken to the operating room on the basis of her painful symptoms and her family history. Unexpectedly, a localized dissection was found in the ascending aorta (see Fig 2), which was too small for imaging detection. Without preemptive surgery, full-fledged dissection would have likely occurred with attendant short and long-term consequences. This case emphasizes that size criteria pertain to asymptomatic patients, and symptomatic patients with aneurysm require resection regardless of size.

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Mesh:

Year:  2005        PMID: 16122497     DOI: 10.1016/j.athoracsur.2004.02.130

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  5 in total

1.  Respecting symptoms in thoracic aortic aneurysm management: a case of symptomatic necrotizing granulomatous aortitis.

Authors:  Gregory A Kuzmik; Adam X Sang; Guoping Cai; Maryann Tranquilli; John A Elefteriades
Journal:  Int J Angiol       Date:  2012-09

2.  Symptoms Matter: A Symptomatic but Radiographically Elusive Ascending Aortic Dissection.

Authors:  Dimitra Papanikolaou; Mohammad A Zafar; Maryam Tanweer; Mahnoor Imran; Mohamed Abdelbaky; Bulat A Ziganshin; John A Elefteriades
Journal:  Int J Angiol       Date:  2018-11-29

Review 3.  Acute Aortic Syndromes: Diagnosis and Treatment.

Authors:  Michael C Murphy; Catherine F Castner; Nicholas T Kouchoukos
Journal:  Mo Med       Date:  2017 Nov-Dec

4.  Mutations in myosin light chain kinase cause familial aortic dissections.

Authors:  Li Wang; Dong-chuan Guo; Jiumei Cao; Limin Gong; Kristine E Kamm; Ellen Regalado; Li Li; Sanjay Shete; Wei-Qi He; Min-Sheng Zhu; Stephan Offermanns; Dawna Gilchrist; John Elefteriades; James T Stull; Dianna M Milewicz
Journal:  Am J Hum Genet       Date:  2010-11-04       Impact factor: 11.025

Review 5.  Transforming growth factor-beta signaling in thoracic aortic aneurysm development: a paradox in pathogenesis.

Authors:  Jeffrey A Jones; Francis G Spinale; John S Ikonomidis
Journal:  J Vasc Res       Date:  2008-09-02       Impact factor: 1.934

  5 in total

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