| Literature DB >> 16122415 |
Dirk Schübeler1, Bryan M Turner.
Abstract
The posttranslational modification of histones by acetylation or methylation regulates chromatin structure and can determine how a DNA sequence is interpreted by, for example, the transcriptional machinery. In this issue of Cell, Pokholok and colleagues (2005) describe a new and reliable genome-wide microarray study of histone modifications and gene expression in yeast. Their epigenetic map can be used to guide further research on the epigenome.Entities:
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Year: 2005 PMID： 16122415 DOI： 10.1016/j.cell.2005.08.007
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582