Literature DB >> 16120281

Antibody-based approaches to diagnosis and characterization of oxidative phosphorylation diseases.

B J Hanson1, M F Marusich, R A Capaldi.   

Abstract

Mitochondrial disorders caused by defects in oxidative phosphorylation function are difficult to diagnose. Here we review the emerging use of antibody-based approaches for this diagnosis. Novel methods involving immunohistochemistry and immunocapture of defective enzymes for characterization are described that add to the arsenal of approaches available.

Entities:  

Year:  2001        PMID: 16120281     DOI: 10.1016/s1567-7249(01)00026-5

Source DB:  PubMed          Journal:  Mitochondrion        ISSN: 1567-7249            Impact factor:   4.160


  1 in total

1.  Metallothionein 2A affects the cell respiration by suppressing the expression of mitochondrial protein cytochrome c oxidase subunit II.

Authors:  Olga Bragina; Karina Gurjanova; Jekaterina Krishtal; Maria Kulp; Niina Karro; Vello Tõugu; Peep Palumaa
Journal:  J Bioenerg Biomembr       Date:  2015-03-27       Impact factor: 2.945

  1 in total

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