Literature DB >> 16120200

Patients at risk of onychomycosis--risk factor identification and active prevention.

A Tosti1, R Hay, R Arenas-Guzmán.   

Abstract

OBJECTIVES: The aims of this workshop were to identify risk factors for onychomycosis and to reach consensus on the management of high-risk groups to allow the development of guidelines to help doctors recognize risk factors that complicate treatment. RESULTS AND
CONCLUSIONS: Previous Trichophyton rubrum infection, older age, abnormal nail morphology, immunodeficiency and genetic factors were identified as risk factors for initial infections. Risk factors for recurrence (relapse and re-infection) are largely the same. The experts agreed that the prevention of onychomycosis and its recurrence should be based on the correct treatment of tinea pedis, screening family members and adequate patient education. In addition, generic management recommendations for each high-risk group were discussed: * Immunosuppressed patients Usual dose and treatment length not appropriate Follow-up required Beware of drug interactions * Diabetics Prophylactic foot care combined with nail treatment Good opportunity for patient education, footwear, foot care, etc. Beware of drug interactions * Psoriatics and patients with abnormal nails Dermatophyte eradication does not restore normal nails * Children High failure rate possibly due to compliance problems.

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Year:  2005        PMID: 16120200     DOI: 10.1111/j.1468-3083.2005.01282.x

Source DB:  PubMed          Journal:  J Eur Acad Dermatol Venereol        ISSN: 0926-9959            Impact factor:   6.166


  18 in total

1.  Evaluation of the morphological effects of TDT 067 (terbinafine in Transfersome) and conventional terbinafine on dermatophyte hyphae in vitro and in vivo.

Authors:  M Ghannoum; N Isham; W Henry; H-A Kroon; S Yurdakul
Journal:  Antimicrob Agents Chemother       Date:  2012-02-21       Impact factor: 5.191

2.  Establishment of a novel model of onychomycosis in rabbits for evaluation of antifungal agents.

Authors:  Tsuyoshi Shimamura; Nobuo Kubota; Saori Nagasaka; Taku Suzuki; Hideki Mukai; Kazutoshi Shibuya
Journal:  Antimicrob Agents Chemother       Date:  2011-05-09       Impact factor: 5.191

3.  Causative Agents of Onychomycosis: A 7-Year Study.

Authors:  Mostafa Chadeganipour; Rasoul Mohammadi
Journal:  J Clin Lab Anal       Date:  2016-04-13       Impact factor: 2.352

Review 4.  Onychomycosis: Practical Approaches to Minimize Relapse and Recurrence.

Authors:  Antonella Tosti; Boni E Elewski
Journal:  Skin Appendage Disord       Date:  2016-09-14

5.  Toenail onychomycosis in a Portuguese geriatric population.

Authors:  N Dias; C Santos; M Portela; N Lima
Journal:  Mycopathologia       Date:  2011-03-02       Impact factor: 2.574

6.  Activity of TDT 067 (terbinafine in Transfersome) against agents of onychomycosis, as determined by minimum inhibitory and fungicidal concentrations.

Authors:  Mahmoud Ghannoum; Nancy Isham; Jacqueline Herbert; William Henry; Sam Yurdakul
Journal:  J Clin Microbiol       Date:  2011-03-16       Impact factor: 5.948

Review 7.  Onychomycosis nailed.

Authors:  M Leelavathi; Mn Noorlaily
Journal:  Malays Fam Physician       Date:  2014-04-30

8.  Onychomycosis and Onychomatricoma.

Authors:  Penelope Kallis; Antonella Tosti
Journal:  Skin Appendage Disord       Date:  2016-04-22

Review 9.  Risk Factors and Comorbidities for Onychomycosis: Implications for Treatment with Topical Therapy.

Authors:  Boni E Elewski; Antonella Tosti
Journal:  J Clin Aesthet Dermatol       Date:  2015-11

Review 10.  The Impact of Onychomycosis on Quality of Life: A Systematic Review of the Available Literature.

Authors:  Aditya K Gupta; Rachel R Mays
Journal:  Skin Appendage Disord       Date:  2018-02-13
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