Literature DB >> 16118113

A Drosophila model of mitochondrial DNA replication: proteins, genes and regulation.

Rafael Garesse1, Laurie S Kaguni.   

Abstract

Mitochondrial biogenesis is a critical process in animal development, cellular homeostasis and aging. Mitochondrial DNA replication is an essential part of this process, and both nuclear and mitochondrial DNA mutations are found to result in mitochondrial dysfunction that leads to developmental defects and delays, aging and disease. Drosophila provides an amenable model system to study mitochondrial biogenesis in normal and disease states. This review provides an overview of current approaches to study the proteins involved in mitochondrial DNA replication, the genes that encode them and their regulation. It also presents a survey of cell and animal models under development to mimic the pathophysiology of human mitochondrial disorders.

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Year:  2005        PMID： 16118113     DOI： 10.1080/15216540500215572

Source DB:  PubMed          Journal:  IUBMB Life        ISSN： 1521-6543            Impact factor:   3.885


  14 in total

1.  The replicative DNA polymerase of herpes simplex virus 1 exhibits apurinic/apyrimidinic and 5'-deoxyribose phosphate lyase activities.

Authors:  Federica Bogani; Paul E Boehmer
Journal:  Proc Natl Acad Sci U S A       Date:  2008-08-11       Impact factor: 11.205

Review 2.  Modeling human mitochondrial diseases in flies.

Authors:  Alvaro Sánchez-Martínez; Ningguang Luo; Paula Clemente; Cristina Adán; Rosana Hernández-Sierra; Pilar Ochoa; Miguel Angel Fernández-Moreno; Laurie S Kaguni; Rafael Garesse
Journal:  Biochim Biophys Acta       Date:  2006-05-13

Review 3.  Heat shock proteins and Drosophila aging.

Authors:  John Tower
Journal:  Exp Gerontol       Date:  2010-09-16       Impact factor: 4.032

Review 4.  Matrix proteases in mitochondrial DNA function.

Authors:  Yuichi Matsushima; Laurie S Kaguni
Journal:  Biochim Biophys Acta       Date:  2011-12-08

5.  Functional characterization of transcription factor motifs using cross-species comparison across large evolutionary distances.

Authors:  Jaebum Kim; Ryan Cunningham; Brian James; Stefan Wyder; Joshua D Gibson; Oliver Niehuis; Evgeny M Zdobnov; Hugh M Robertson; Gene E Robinson; John H Werren; Saurabh Sinha
Journal:  PLoS Comput Biol       Date:  2010-01-29       Impact factor: 4.475

6.  The Drosophila HNF4 nuclear receptor promotes glucose-stimulated insulin secretion and mitochondrial function in adults.

Authors:  William E Barry; Carl S Thummel
Journal:  Elife       Date:  2016-05-17       Impact factor: 8.140

7.  Mitochondrial transcription factor B2 is essential for metabolic function in Drosophila melanogaster development.

Authors:  Cristina Adán; Yuichi Matsushima; Rosana Hernández-Sierra; Raquel Marco-Ferreres; Miguel Angel Fernández-Moreno; Emiliano González-Vioque; Manuel Calleja; Juan J Aragón; Laurie S Kaguni; Rafael Garesse
Journal:  J Biol Chem       Date:  2008-02-28       Impact factor: 5.157

8.  Distinctive mitochondrial genome of Calanoid copepod Calanus sinicus with multiple large non-coding regions and reshuffled gene order: useful molecular markers for phylogenetic and population studies.

Authors:  Wang Minxiao; Sun Song; Li Chaolun; Shen Xin
Journal:  BMC Genomics       Date:  2011-01-27       Impact factor: 3.969

9.  Mitochondrial genome deletions and minicircles are common in lice (Insecta: Phthiraptera).

Authors:  Stephen L Cameron; Kazunori Yoshizawa; Atsushi Mizukoshi; Michael F Whiting; Kevin P Johnson
Journal:  BMC Genomics       Date:  2011-08-04       Impact factor: 3.969

10.  Expression profiling of attenuated mitochondrial function identifies retrograde signals in Drosophila.

Authors:  William A Freije; Sudip Mandal; Utpal Banerjee
Journal:  G3 (Bethesda)       Date:  2012-08-01       Impact factor: 3.154
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