Ellis G Farstvedt1, Dean A Hendrickson. 1. Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.
Abstract
OBJECTIVE: To compare intraoperative pain responses following intraovarian versus mesovarian injection of lidocaine in mares undergoing laparoscopic ovariectomy. DESIGN: Randomized controlled trial. ANIMALS: 15 mares between 4 and 20 years old. PROCEDURE: Standard bilateral laparoscopic ovariectomy was performed. Prior to manipulation of the ovary, 2% lidocaine (10 mL) was injected into the ovary and saline (0.9% NaCI) solution (10 mL) was injected into the mesovarium on 1 side, with saline solution (10 mL) injected into the ovary and 2% lidocaine (10 mL) injected into the mesovarium on the other side. Presence (yes vs no) and severity (visual analogue scale) of pain were scored at 5 times (grasping of the ovary, dissection of the mesosalpinx, tightening of the first loop ligature, tightening of the second loop ligature, and transection of the ovarian pedicle) by 2 individuals blinded to treatment and each other's observations. RESULTS: During 4 of the 5 observation periods, significantly fewer mares had signs of pain following mesovarian injection of lidocaine, and during 2 of the 5 observation periods, visual analogue scale score was significantly lower. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that mesovarian injection of lidocaine is associated with significantly lower pain responses, compared with intraovarian injection, in horses undergoing laparoscopic ovariectomy.
OBJECTIVE: To compare intraoperative pain responses following intraovarian versus mesovarian injection of lidocaine in mares undergoing laparoscopic ovariectomy. DESIGN: Randomized controlled trial. ANIMALS: 15 mares between 4 and 20 years old. PROCEDURE: Standard bilateral laparoscopic ovariectomy was performed. Prior to manipulation of the ovary, 2% lidocaine (10 mL) was injected into the ovary and saline (0.9% NaCI) solution (10 mL) was injected into the mesovarium on 1 side, with saline solution (10 mL) injected into the ovary and 2% lidocaine (10 mL) injected into the mesovarium on the other side. Presence (yes vs no) and severity (visual analogue scale) of pain were scored at 5 times (grasping of the ovary, dissection of the mesosalpinx, tightening of the first loop ligature, tightening of the second loop ligature, and transection of the ovarian pedicle) by 2 individuals blinded to treatment and each other's observations. RESULTS: During 4 of the 5 observation periods, significantly fewer mares had signs of pain following mesovarian injection of lidocaine, and during 2 of the 5 observation periods, visual analogue scale score was significantly lower. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that mesovarian injection of lidocaine is associated with significantly lower pain responses, compared with intraovarian injection, in horses undergoing laparoscopic ovariectomy.