| Literature DB >> 16116134 |
J Sastre-Garriga1, G T Ingle, M Rovaris, N Téllez, B Jasperse, D R Altmann, B Benedetti, V L Stevenson, M Cercignani, S M Leary, F Barkhof, B Brochet, V Dousset, M Filippi, X Montalban, N F Kalkers, C H Polman, A Rovira, D H Miller, A J Thompson.
Abstract
The authors sought to identify clinical and MRI predictors of outcome in primary progressive multiple sclerosis (PPMS). Clinical and MRI assessments were performed at baseline and 2 and 5 years (clinical only). At baseline, disease duration, expanded disability status scale (EDSS) and brain volume predicted outcome. Adding short-term change variables, baseline EDSS, changes in T2* lesion load and cord area, and number of new lesions were predictive. Clinical and MRI variables predict long-term outcome in PPMS.Entities:
Mesh：
Year: 2005 PMID： 16116134 DOI： 10.1212/01.wnl.0000173061.12776.1f
Source DB: PubMed Journal: Neurology ISSN： 0028-3878 Impact factor: 9.910