| Literature DB >> 16116132 |
Marguerite Wieler1, Richard Camicioli, C Allyson Jones, W R Wayne Martin.
Abstract
Freezing of gait (FOG) is common in patients with Parkinson disease (PD) and responds poorly to medical treatment. Botulinum toxin A (BTX-A) injections into calf muscles decreased FOG in previous open-label studies. The authors conducted a randomized double-blind placebo-controlled crossover study of BTX-A vs placebo in 12 subjects with PD and FOG. No significant improvement with BTX-A was found using subjective and objective measures.Entities:
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Year: 2005 PMID： 16116132 DOI： 10.1212/01.wnl.0000172930.63669.c8
Source DB: PubMed Journal: Neurology ISSN： 0028-3878 Impact factor: 9.910