Literature DB >> 16115778

Urinary interleukin-8 is elevated in urinary tract infections independently of the causative germs.

Olivier Oregioni1, Pascal Delaunay, Pascal Bruna, Alice Gaudart, Emmanuel Lemichez, Patrice Boquet, Luce Landraud.   

Abstract

Interleukin-8 elevation in urine during urinary tract infections (UTIs) has been documented for different uropathogenic germs in 85 patients. We showed that for 17 different isolates, IL-8 was increased in 92% of UTIs with an average value of 627 pg/ml for infected, as compared to 45 pg/ml for uninfected patients. We suggest that the high negative predictive value of the IL-8 urine assay could be useful to eliminate UTIs in routine screenings.

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Year:  2005        PMID: 16115778     DOI: 10.1016/j.cyto.2005.06.009

Source DB:  PubMed          Journal:  Cytokine        ISSN: 1043-4666            Impact factor:   3.861


  9 in total

1.  Genome-wide mapping of cystitis due to Streptococcus agalactiae and Escherichia coli in mice identifies a unique bladder transcriptome that signifies pathogen-specific antimicrobial defense against urinary tract infection.

Authors:  Chee K Tan; Alison J Carey; Xiangqin Cui; Richard I Webb; Deepak Ipe; Michael Crowley; Allan W Cripps; William H Benjamin; Kimberly B Ulett; Mark A Schembri; Glen C Ulett
Journal:  Infect Immun       Date:  2012-06-25       Impact factor: 3.441

2.  Characterization of a novel murine model of Staphylococcus saprophyticus urinary tract infection reveals roles for Ssp and SdrI in virulence.

Authors:  Kimberly A Kline; Molly A Ingersoll; Hailyn V Nielsen; Türkan Sakinc; Birgitta Henriques-Normark; Sören Gatermann; Michael G Caparon; Scott J Hultgren
Journal:  Infect Immun       Date:  2010-02-22       Impact factor: 3.441

3.  Serum and Urine Interleukin-6 and Interleukin-8 Levels Do Not Differentiate Acute Pyelonephritis from Lower Urinary Tract Infections in Children.

Authors:  Maysoun Al Rushood; Amal Al-Eisa; Rajaa' Al-Attiyah
Journal:  J Inflamm Res       Date:  2020-10-28

4.  Novel biomarkers for the diagnosis of urinary tract infection-a systematic review.

Authors:  Neha Nanda; Manisha Juthani-Mehta
Journal:  Biomark Insights       Date:  2009-08-05

5.  Urine Cytokine and Chemokine Levels Predict Urinary Tract Infection Severity Independent of Uropathogen, Urine Bacterial Burden, Host Genetics, and Host Age.

Authors:  Chelsie E Armbruster; Sara N Smith; Lona Mody; Harry L T Mobley
Journal:  Infect Immun       Date:  2018-08-22       Impact factor: 3.441

6.  Cytokines in urine in elderly subjects with acute cystitis and asymptomatic bacteriuria.

Authors:  Nils Rodhe; Sture Löfgren; Jan Strindhall; Andreas Matussek; Sigvard Mölstad
Journal:  Scand J Prim Health Care       Date:  2009       Impact factor: 2.581

7.  G-CSF induction early in uropathogenic Escherichia coli infection of the urinary tract modulates host immunity.

Authors:  Molly A Ingersoll; Kimberly A Kline; Hailyn V Nielsen; Scott J Hultgren
Journal:  Cell Microbiol       Date:  2008-08-26       Impact factor: 3.715

8.  Male kidney allograft recipients at risk for urinary tract infection?

Authors:  Gerold Thölking; Katharina Schuette-Nuetgen; Thomas Vogl; Ulrich Dobrindt; Barbara C Kahl; Marcus Brand; Hermann Pavenstädt; Barbara Suwelack; Raphael Koch; Stefan Reuter
Journal:  PLoS One       Date:  2017-11-16       Impact factor: 3.240

9.  Helicobacter pylori counteracts the apoptotic action of its VacA toxin by injecting the CagA protein into gastric epithelial cells.

Authors:  Amanda Oldani; Mireille Cormont; Veronique Hofman; Valentina Chiozzi; Olivier Oregioni; Alexandra Canonici; Anna Sciullo; Patrizia Sommi; Alessia Fabbri; Vittorio Ricci; Patrice Boquet
Journal:  PLoS Pathog       Date:  2009-10-02       Impact factor: 6.823

  9 in total

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