Literature DB >> 1611553

Isolation and biological activities of endotoxin from Leptospira interrogans.

L de Souza1, M C Koury.   

Abstract

Endotoxins extracted with ethylenediaminetetraacetate (EDTA) from Leptospira interrogans serovars icterohaemorrhagiae and canicola and Leptospira biflexa serovar patoc were tested for various biological activities characteristic of endotoxins. The presence of lipopolysaccharide biological activity was demonstrated by the Limulus amoebocyte lysate test, pyrogenicity in rabbits, complement interaction inhibiting the erythrocyte lysis, and chicken-embryo lethality. The lipopolysaccharides did not induce the local Shwartzman reaction. The lipopolysaccharides of serovars icterohaemorrhagiae and canicola were immunogenic in rabbits and were cytotoxic to chicken-embryo fibroblasts.

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Year:  1992        PMID： 1611553     DOI： 10.1139/m92-047

Source DB:  PubMed          Journal:  Can J Microbiol        ISSN： 0008-4166            Impact factor:   2.419


  8 in total

1.  Purification and characterization of a Na+, K+ ATPase inhibitor found in an endotoxin of Leptospira interrogans.

Authors:  P Burth; M Younes-Ibrahim; F H Gonçalez; E R Costa; M V Faria
Journal:  Infect Immun       Date:  1997-04       Impact factor: 3.441

2.  InvA protein is a Nudix hydrolase required for infection by pathogenic Leptospira in cell lines and animals.

Authors:  Yihui Luo; Yan Liu; Dexter Sun; David M Ojcius; Jinfang Zhao; Xuai Lin; Dong Wu; Rongguang Zhang; Ming Chen; Lanjuan Li; Jie Yan
Journal:  J Biol Chem       Date:  2011-08-23       Impact factor: 5.157

3.  Biological characterization of lipopolysaccharide from Treponema pectinovorum.

Authors:  Lakshmyya Kesavalu; Clinton W Falk; Kenneth J Davis; Michelle J Steffen; Xiaoping Xu; Stanley C Holt; Jeffrey L Ebersole
Journal:  Infect Immun       Date:  2002-01       Impact factor: 3.441

4.  Genome features of Leptospira interrogans serovar Copenhageni.

Authors:  A L T O Nascimento; S Verjovski-Almeida; M A Van Sluys; C B Monteiro-Vitorello; L E A Camargo; L A Digiampietri; R A Harstkeerl; P L Ho; M V Marques; M C Oliveira; J C Setubal; D A Haake; E A L Martins
Journal:  Braz J Med Biol Res       Date:  2004-03-23       Impact factor: 2.590

5.  Potent innate immune response to pathogenic leptospira in human whole blood.

Authors:  Marga G A Goris; Jiri F P Wagenaar; Rudy A Hartskeerl; Eric C M van Gorp; Simone Schuller; Avril M Monahan; Jarlath E Nally; Tom van der Poll; Cornelis van 't Veer
Journal:  PLoS One       Date:  2011-03-31       Impact factor: 3.240

6.  Thrombocytopenia in the experimental leptospirosis of guinea pig is not related to disseminated intravascular coagulation.

Authors:  Hong-Liang Yang; Xu-Cheng Jiang; Xiang-Yan Zhang; Wen-Jun Li; Bao-Yu Hu; Guo-Ping Zhao; Xiao-Kui Guo
Journal:  BMC Infect Dis       Date:  2006-02-02       Impact factor: 3.090

7.  MicroRNAs Regulated by the LPS/TLR2 Immune Axis as Bona Fide Biomarkers for Diagnosis of Acute Leptospirosis.

Authors:  Charles Solomon Akino Mercy; Natarajaseenivasan Suriya Muthukumaran; Prema Velusamy; Palanisamy Bothammal; Krishnamoorthi Sumaiya; Perumal Saranya; Dianne Langford; Santhanam Shanmughapriya; Kalimuthusamy Natarajaseenivasan
Journal:  mSphere       Date:  2020-07-15       Impact factor: 4.389

8.  Bovine endometrial cells do not mount an inflammatory response to Leptospira.

Authors:  Paula C C Molinari; Jarlath E Nally; John J Bromfield
Journal:  Reprod Fertil       Date:  2021-07-13
  8 in total

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