Literature DB >> 16113736

The vicinal F-C-C-F moiety as a tool for influencing peptide conformation.

Martin Schüler1, David O'hagan, Alexandra M Z Slawin.   

Abstract

Diastereoisomers of bis(amino acid amides) of 2,3-difluorosuccinic acid have been prepared and the erythro- and threo-isomers display very different conformations.

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Year:  2005        PMID： 16113736     DOI： 10.1039/b506010a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  8 in total

1.  Catalytic, Enantioselective 1,2-Difluorination of Cinnamamides.

Authors:  Moriana K Haj; Steven M Banik; Eric N Jacobsen
Journal:  Org Lett       Date:  2019-04-09       Impact factor: 6.005

2.  Synthesis of mixed opioid affinity cyclic endomorphin-2 analogues with fluorinated phenylalanines.

Authors:  Justyna Piekielna; Renata Perlikowska; Jean Claude do-Rego; Jean-Luc do-Rego; Maria Camilla Cerlesi; Girolamo Calo; Alicja Kluczyk; Krzysztof Łapiński; Csaba Tömböly; Anna Janecka
Journal:  ACS Med Chem Lett       Date:  2015-04-03       Impact factor: 4.345

3.  Hydroxy-directed fluorination of remote unactivated C(sp3)-H bonds: a new age of diastereoselective radical fluorination.

Authors:  Stefan Andrew Harry; Michael Richard Xiang; Eric Holt; Andrea Zhu; Fereshte Ghorbani; Dhaval Patel; Thomas Lectka
Journal:  Chem Sci       Date:  2022-05-30       Impact factor: 9.969

4.  The C-F bond as a conformational tool in organic and biological chemistry.

Authors:  Luke Hunter
Journal:  Beilstein J Org Chem       Date:  2010-04-20       Impact factor: 2.883

5.  Synthesis and crystallographic analysis of meso-2,3-difluoro-1,4-butanediol and meso-1,4-dibenzyloxy-2,3-difluorobutane.

Authors:  Bruno Linclau; Leo Leung; Jean Nonnenmacher; Graham Tizzard
Journal:  Beilstein J Org Chem       Date:  2010-06-08       Impact factor: 2.883

6.  The vicinal difluoro motif: The synthesis and conformation of erythro- and threo- diastereoisomers of 1,2-difluorodiphenylethanes, 2,3-difluorosuccinic acids and their derivatives.

Authors:  David O'Hagan; Henry S Rzepa; Martin Schüler; Alexandra M Z Slawin
Journal:  Beilstein J Org Chem       Date:  2006-10-02       Impact factor: 2.883

7.  Homologated amino acids with three vicinal fluorines positioned along the backbone: development of a stereoselective synthesis.

Authors:  Raju Cheerlavancha; Ahmed Ahmed; Yun Cheuk Leung; Aggie Lawer; Qing-Quan Liu; Marina Cagnes; Hee-Chan Jang; Xiang-Guo Hu; Luke Hunter
Journal:  Beilstein J Org Chem       Date:  2017-11-01       Impact factor: 2.883

8.  Electrochemical Vicinal Difluorination of Alkenes: Scalable and Amenable to Electron-Rich Substrates.

Authors:  Sayad Doobary; Alexi T Sedikides; Henry P Caldora; Darren L Poole; Alastair J J Lennox
Journal:  Angew Chem Int Ed Engl       Date:  2019-11-28       Impact factor: 15.336
  8 in total

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