Literature DB >> 16113417

Mechanisms of bronchial hyperreactivity in asthma and chronic obstructive pulmonary disease.

Diana C Grootendorst1, Klaus F Rabe.   

Abstract

Bronchial hyperreactivity has long been recognized as a hallmark of chronic asthma. Less is known about the prevalence and mechanisms of hyperreactivity in chronic obstructive pulmonary disease (COPD). Currently, it is unclear whether the role and mechanisms of hyperreactivity are similar in patients with asthma and COPD or whether the underlying pathophysiologic abnormalities are different for both diseases. The aim of this review is to present an overview of current knowledge of the mechanisms of bronchial hyperreactivity in asthma and COPD.

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Year:  2004        PMID： 16113417     DOI： 10.1513/pats.2306025

Source DB:  PubMed          Journal:  Proc Am Thorac Soc        ISSN： 1546-3222


  13 in total

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