Literature DB >> 16113343

Analysis of cellular phenotypes that mediate genetic resistance to tuberculosis using a radiation bone marrow chimera approach.

Konstantin B Majorov1, Evgeny B Eruslanov, Elvira I Rubakova, Tatiana K Kondratieva, Alexander S Apt.   

Abstract

Adoptive transfer of bone marrow cells from tuberculosis-resistant (I/St x A/Sn)F(1) donor mice into lethally irradiated susceptible I/St recipients changed their phenotype following infection with virulent Mycobacterium tuberculosis. Compared to I/St-->I/St control animals, F(1)-->I/St chimeras demonstrated (i) prolonged survival time, (ii) increased antimycobacterial function of lung macrophages, (iii) elevated gamma interferon production by lung cells, and (iv) decreased infiltration of the lungs with CD4(+) and CD8(+) T cells and Ly-6G(+) neutrophils.

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Year:  2005        PMID： 16113343      PMCID： PMC1231063          DOI： 10.1128/IAI.73.9.6174-6178.2005

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  28 in total

Review 1.  Immunology of tuberculosis.

Authors:  J L Flynn; J Chan
Journal:  Annu Rev Immunol       Date:  2001       Impact factor: 28.527

2.  Human macrophage activation programs induced by bacterial pathogens.

Authors:  Gerard J Nau; Joan F L Richmond; Ann Schlesinger; Ezra G Jennings; Eric S Lander; Richard A Young
Journal:  Proc Natl Acad Sci U S A       Date:  2002-01-22       Impact factor: 11.205

3.  Regulation of gene expression in mouse macrophages stimulated with bacterial CpG-DNA and lipopolysaccharide.

Authors:  Jian Jun Gao; Veronica Diesl; Tatiana Wittmann; David C Morrison; John L Ryan; Stefanie N Vogel; Maximillian T Follettie
Journal:  J Leukoc Biol       Date:  2002-12       Impact factor: 4.962

Review 4.  The battle of two genomes: genetics of bacterial host/pathogen interactions in mice.

Authors:  A Lengeling; K Pfeffer; R Balling
Journal:  Mamm Genome       Date:  2001-04       Impact factor: 2.957

5.  Genetic control of resistance to experimental infection with virulent Mycobacterium tuberculosis.

Authors:  I Kramnik; W F Dietrich; P Demant; B R Bloom
Journal:  Proc Natl Acad Sci U S A       Date:  2000-07-18       Impact factor: 11.205

6.  Microarray analysis of mRNA levels from RAW264.7 macrophages infected with Brucella abortus.

Authors:  Linda Eskra; Angela Mathison; Gary Splitter
Journal:  Infect Immun       Date:  2003-03       Impact factor: 3.441

7.  Susceptibility to tuberculosis: a locus on mouse chromosome 19 (Trl-4) regulates Mycobacterium tuberculosis replication in the lungs.

Authors:  Loukia-Maria Mitsos; Lon R Cardon; Lynn Ryan; Ronald LaCourse; Robert J North; Philippe Gros
Journal:  Proc Natl Acad Sci U S A       Date:  2003-05-09       Impact factor: 11.205

8.  Multigenic control of disease severity after virulent Mycobacterium tuberculosis infection in mice.

Authors:  Fabio Sánchez; Tatiana V Radaeva; Boris V Nikonenko; Ann-Sophie Persson; Selim Sengul; Martin Schalling; Erwin Schurr; Alexander S Apt; Catharina Lavebratt
Journal:  Infect Immun       Date:  2003-01       Impact factor: 3.441

9.  Comparative analysis of T lymphocytes recovered from the lungs of mice genetically susceptible, resistant, and hyperresistant to Mycobacterium tuberculosis-triggered disease.

Authors:  I V Lyadova; E B Eruslanov; S V Khaidukov; V V Yeremeev; K B Majorov; A V Pichugin; B V Nikonenko; T K Kondratieva; A S Apt
Journal:  J Immunol       Date:  2000-11-15       Impact factor: 5.422

10.  Different innate ability of I/St and A/Sn mice to combat virulent Mycobacterium tuberculosis: phenotypes expressed in lung and extrapulmonary macrophages.

Authors:  Konstantin B Majorov; Irina V Lyadova; Tatiana K Kondratieva; Eugeny B Eruslanov; Elvira I Rubakova; Marianna O Orlova; Vladimir V Mischenko; Alexander S Apt
Journal:  Infect Immun       Date:  2003-02       Impact factor: 3.441
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  5 in total

Review 1.  Cytokines and Chemokines in Mycobacterium tuberculosis Infection.

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Review 2.  The Goldilocks model of immune symbiosis with Mycobacteria and Candida colonizers.

Authors:  Richard T Robinson; Anna R Huppler
Journal:  Cytokine       Date:  2017-05-29       Impact factor: 3.861

3.  Genetic and functional characterization of the mouse Trl3 locus in defense against tuberculosis.

Authors:  Jean-François Marquis; Ronald Lacourse; Lynn Ryan; Robert J North; Philippe Gros
Journal:  J Immunol       Date:  2009-03-15       Impact factor: 5.422

4.  Constitutive differences in gene expression profiles parallel genetic patterns of susceptibility to tuberculosis in mice.

Authors:  Marianna O Orlova; Konstantin B Majorov; Irina V Lyadova; Eugenii B Eruslanov; Cyr E M'lan; Celia M T Greenwood; Erwin Schurr; Alexander S Apt
Journal:  Infect Immun       Date:  2006-06       Impact factor: 3.441

5.  Generation of bone marrow chimeras using X-ray irradiation: comparison to cesium irradiation and use in immunotherapy.

Authors:  Jason Eng; Jessica Orf; Kristy Perez; Deepali Sawant; Jason DeVoss
Journal:  J Biol Methods       Date:  2020-02-17
  5 in total

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