Literature DB >> 16113135

Prolonged QT interval in an infant of a fluoxetine treated mother.

G Dubnov1, R Fogelman, P Merlob.   

Abstract

Fluoxetine is an antidepressant drug, only recently discovered to be a QT interval prolonging agent. The first case is presented of an infant of a mother treated with fluoxetine during pregnancy who had a transiently prolonged QTc interval, concluded to be drug induced. Clinical and electrocardiographic monitoring of newborns of antidepressant treated mothers is needed.

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Year:  2005        PMID: 16113135      PMCID: PMC1720576          DOI: 10.1136/adc.2004.064618

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN: 0003-9888            Impact factor:   3.791


  6 in total

Review 1.  The QT interval and psychotropic medications in children: recommendations for clinicians.

Authors:  Paul McNally; Fiona McNicholas; Paul Oslizlok
Journal:  Eur Child Adolesc Psychiatry       Date:  2006-08-29       Impact factor: 4.785

2.  Drug-induced long QT syndrome: hERG K+ channel block and disruption of protein trafficking by fluoxetine and norfluoxetine.

Authors:  S Rajamani; L L Eckhardt; C R Valdivia; C A Klemens; B M Gillman; C L Anderson; K M Holzem; B P Delisle; B D Anson; J C Makielski; C T January
Journal:  Br J Pharmacol       Date:  2006-09-11       Impact factor: 8.739

Review 3.  Serotonin reuptake inhibitor-induced perinatal complications.

Authors:  Salvatore Gentile
Journal:  Paediatr Drugs       Date:  2007       Impact factor: 3.022

Review 4.  QTc interval prolongation and torsade de pointes associated with second-generation antipsychotics and antidepressants: a comprehensive review.

Authors:  Mehrul Hasnain; W Victor R Vieweg
Journal:  CNS Drugs       Date:  2014-10       Impact factor: 5.749

5.  Combined hERG channel inhibition and disruption of trafficking in drug-induced long QT syndrome by fluoxetine: a case-study in cardiac safety pharmacology.

Authors:  J C Hancox; J S Mitcheson
Journal:  Br J Pharmacol       Date:  2006-09-11       Impact factor: 8.739

6.  Sudden death of cardiac origin and psychotropic drugs.

Authors:  Quadiri Timour; Dominique Frassati; Jacques Descotes; Philippe Chevalier; Georges Christé; Mohamed Chahine
Journal:  Front Pharmacol       Date:  2012-05-10       Impact factor: 5.810

  6 in total

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