Literature DB >> 16111629

TLR ignores methylated RNA?

Ken J Ishii1, Shizuo Akira.   

Abstract

CpG methylation of DNA silences TLR9-mediated innate immune recognition. In this issue of Immunity, Kariko et al (2005) suggest that the innate immune recognition of RNA by TLR3, TLR7, or TLR8 is in fact controlled by modification of nucleotides, including methylation.

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Year:  2005        PMID： 16111629     DOI： 10.1016/j.immuni.2005.08.003

Source DB:  PubMed          Journal:  Immunity        ISSN： 1074-7613            Impact factor:   31.745


  11 in total

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Authors:  Man Yu; Stewart J Levine
Journal:  Cytokine Growth Factor Rev       Date:  2011-04-03       Impact factor: 7.638

2.  Bacterial RNA induces myocyte cellular dysfunction through the activation of PKR.

Authors:  Farag Bleiblo; Paul Michael; Danielle Brabant; Chilakamarti V Ramana; Tc Tai; Mazen Saleh; Joseph E Parrillo; Anand Kumar; Aseem Kumar
Journal:  J Thorac Dis       Date:  2012-04-01       Impact factor: 2.895

3.  Efficient RNA virus control in Drosophila requires the RNA methyltransferase Dnmt2.

Authors:  Zeljko Durdevic; Katharina Hanna; Beth Gold; Tim Pollex; Sara Cherry; Frank Lyko; Matthias Schaefer
Journal:  EMBO Rep       Date:  2013-02-01       Impact factor: 8.807

Review 4.  Toll or toll-free adjuvant path toward the optimal vaccine development.

Authors:  Ken J Ishii; Shizuo Akira
Journal:  J Clin Immunol       Date:  2007-03-17       Impact factor: 8.317

Review 5.  Sensors of the innate immune system: their link to rheumatic diseases.

Authors:  Argyrios N Theofilopoulos; Rosana Gonzalez-Quintial; Brian R Lawson; Yi T Koh; Michael E Stern; Dwight H Kono; Bruce Beutler; Roberto Baccala
Journal:  Nat Rev Rheumatol       Date:  2010-02-09       Impact factor: 20.543

Review 6.  Recent Developments in mRNA-Based Protein Supplementation Therapy to Target Lung Diseases.

Authors:  Itishri Sahu; A K M Ashiqul Haque; Brian Weidensee; Petra Weinmann; Michael S D Kormann
Journal:  Mol Ther       Date:  2019-03-06       Impact factor: 11.454

7.  Triggering of RNA interference with RNA-RNA, RNA-DNA, and DNA-RNA nanoparticles.

Authors:  Kirill A Afonin; Mathias Viard; Ioannis Kagiampakis; Christopher L Case; Marina A Dobrovolskaia; Jen Hofmann; Ashlee Vrzak; Maria Kireeva; Wojciech K Kasprzak; Vineet N KewalRamani; Bruce A Shapiro
Journal:  ACS Nano       Date:  2014-12-18       Impact factor: 15.881

Review 8.  The Critical Contribution of Pseudouridine to mRNA COVID-19 Vaccines.

Authors:  Pedro Morais; Hironori Adachi; Yi-Tao Yu
Journal:  Front Cell Dev Biol       Date:  2021-11-04

9.  The toll-Like receptor adaptor TRIF contributes to otitis media pathogenesis and recovery.

Authors:  Anke Leichtle; Michelle Hernandez; Kwang Pak; Nicholas J Webster; Stephen I Wasserman; Allen F Ryan
Journal:  BMC Immunol       Date:  2009-08-05       Impact factor: 3.615

10.  Chemically modified RNA activated matrices enhance bone regeneration.

Authors:  Satheesh Elangovan; Behnoush Khorsand; Anh-Vu Do; Liu Hong; Alexander Dewerth; Michael Kormann; Ryan D Ross; D Rick Sumner; Chantal Allamargot; Aliasger K Salem
Journal:  J Control Release       Date:  2015-09-28       Impact factor: 11.467
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