Literature DB >> 16111

In vitro adsortpion of acetaminophen onto activated charcoal.

C A Bainbridge, E L Kelly, W D Walking.   

Abstract

In vitro experiments supported in vivo evidence that activated charcoal is effective in adsorbing acetaminophen. In the physiologic pH range, adsorption was rapid and pH independent. Adsorption, however, was dependent upon the quantity of activated charcoal employed, becoming more complete as the quantity of activated charcoal was increased.

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Year:  1977        PMID： 16111     DOI： 10.1002/jps.2600660405

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN： 0022-3549            Impact factor:   3.534


  6 in total

1.  Comparative antidotal efficacy of activated charcoal tablets, capsules and suspension in healthy volunteers.

Authors:  H P Remmert; M Olling; W Slob; W F van der Giesen; A van Dijk; A G Rauws
Journal:  Eur J Clin Pharmacol       Date:  1990       Impact factor: 2.953

Review 2.  Clinical pharmacokinetics of oral activated charcoal in acute intoxications.

Authors:  P J Neuvonen
Journal:  Clin Pharmacokinet       Date:  1982 Nov-Dec       Impact factor: 6.447

3.  Age-related pseudocapillarization of the liver sinusoidal endothelium impairs the hepatic clearance of acetaminophen in rats.

Authors:  Sarah J Mitchell; Aniko Huizer-Pajkos; Victoria C Cogger; Andrew J McLachlan; David G Le Couteur; Brett Jones; Rafael de Cabo; Sarah N Hilmer
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2011-02-07       Impact factor: 6.053

4.  A ready-to-use activated charcoal mixture. Adsorption studies in vitro and in dogs: its influence on the intestinal secretion of theophylline in a rat model.

Authors:  C M Rademaker; A van Dijk; M H de Vries; F Kadir; J H Glerum
Journal:  Pharm Weekbl Sci       Date:  1989-04-28

Review 5.  Oral activated charcoal in the treatment of intoxications. Role of single and repeated doses.

Authors:  P J Neuvonen; K T Olkkola
Journal:  Med Toxicol Adverse Drug Exp       Date:  1988 Jan-Dec

6.  A comparison of the efficacy of gastric lavage, ipecacuanha and activated charcoal in the emergency management of paracetamol overdose.

Authors:  T J Underhill; M K Greene; A F Dove
Journal:  Arch Emerg Med       Date:  1990-09
  6 in total

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