Literature DB >> 16110122

Surgery for colorectal cancer in a low-volume unit: assessment of key issues in the achievement of acceptable clinical results.

Hannu Paimela1, Outi Lindström, Timo Tomminen, Mauri Iivonen, Esa Könönen, Pekka Kuusanmäki.   

Abstract

BACKGROUND: The maintenance of modern therapeutic principles requires a proper case load to achieve acceptable surgical results. This may obligate administrative reorganization to overcome these problems and to provide an adequate level of cancer surgery. AIM: To assess the surgical results of patients coming for surgery for colorectal cancer in a low-volume non-academic unit during the past 15 yr.
METHODS: 458 consecutive patients referred for surgery between 1988 and 2001 in Kanta-Häme Central Hospital in Finland were analyzed regarding their disease, mode of surgery, and the immediate and long-term result. The data were collected from patient journals and from the National Centre of Statistics and analyzed in two successive periods.
RESULTS: The number of patients with a localized disease (Dukes A + Dukes B) decreased during the followup from 49% to 45%. A curative procedure was achieved in 68% in the first half and in 73% in the second half of the observation period. The immediate mortality was 5% and 2% in the two periods, respectively. The corrected 5-year survival according to the Dukes Classification was 92% (A), 69% (B), 41% (C ), and 6% (D). In curative surgery for rectal cancer, the incidences of local recurrence decreased from 21% to 9% (NS) and the use of permanent colostomy from 59 to 42% (NS).
CONCLUSIONS: Acceptable immediate and long-term results in curative surgery for colorectal cancer can be achieved in a low-volume surgical unit. Nevertheless, owing to the low volume, the improvement of the results obligates team-based institutional specialization and careful consideration about the extensiveness of the primary procedure in case of cancer obstruction.

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Year:  2005        PMID: 16110122     DOI: 10.1385/IJGC:35:3:205

Source DB:  PubMed          Journal:  Int J Gastrointest Cancer        ISSN: 1537-3649


  28 in total

1.  Prognostic significance of the circumferential resection margin following total mesorectal excision for rectal cancer.

Authors:  A Wibe; P R Rendedal; E Svensson; J Norstein; T J Eide; H E Myrvold; O Søreide
Journal:  Br J Surg       Date:  2002-03       Impact factor: 6.939

2.  Surgeon-related factors and outcome in rectal cancer.

Authors:  G A Porter; C L Soskolne; W W Yakimets; S C Newman
Journal:  Ann Surg       Date:  1998-02       Impact factor: 12.969

3.  Anterior resection controls cancer of the rectum as well as abdominoperineal excision.

Authors:  T E Pakkastie; P E Luukkonen; H J Järvinen
Journal:  Eur J Surg       Date:  1995-11

4.  Effect of a surgical training programme on outcome of rectal cancer in the County of Stockholm. Stockholm Colorectal Cancer Study Group, Basingstoke Bowel Cancer Research Project.

Authors:  A L Martling; T Holm; L E Rutqvist; B J Moran; R J Heald; B Cedemark
Journal:  Lancet       Date:  2000-07-08       Impact factor: 79.321

5.  A randomised study of screening for colorectal cancer using faecal occult blood testing: results after 13 years and seven biennial screening rounds.

Authors:  O D Jørgensen; O Kronborg; C Fenger
Journal:  Gut       Date:  2002-01       Impact factor: 23.059

6.  Rectal cancer: the Basingstoke experience of total mesorectal excision, 1978-1997.

Authors:  R J Heald; B J Moran; R D Ryall; R Sexton; J K MacFarlane
Journal:  Arch Surg       Date:  1998-08

7.  Changing distribution of primary cancers in the large bowel.

Authors:  J B Rhodes; F F Holmes; G M Clark
Journal:  JAMA       Date:  1977-10-10       Impact factor: 56.272

8.  Changes in colorectal cancer during a 20-year period: an extended report from the multi-institutional registry of large bowel cancer, Japan.

Authors:  Kenjiro Kotake; Satoshi Honjo; Kenichi Sugihara; Tomoyuki Kato; Susumu Kodaira; Takashi Takahashi; Masayuki Yasutomi; Tetsuichiro Muto; Yasuo Koyama
Journal:  Dis Colon Rectum       Date:  2003-10       Impact factor: 4.585

9.  The mesorectum in rectal cancer surgery--the clue to pelvic recurrence?

Authors:  R J Heald; E M Husband; R D Ryall
Journal:  Br J Surg       Date:  1982-10       Impact factor: 6.939

10.  Trends in subsite distribution of colorectal cancers and polyps from the Vaud Cancer Registry.

Authors:  F Levi; L Randimbison; C La Vecchia
Journal:  Cancer       Date:  1993-07-01       Impact factor: 6.860

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  1 in total

1.  What factors influence 10-year survival after curative resection of a colorectal carcinoma?

Authors:  Torsten Ueberrueck; Christine Wurst; Falk Rauchfuß; Thomas Knösel; Utz Settmacher; Annelore Altendorf-Hofmann
Journal:  World J Surg       Date:  2013-10       Impact factor: 3.352

  1 in total

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