Literature DB >> 16109967

OpsX from Haemophilus influenzae represents a novel type of heptosyltransferase I in lipopolysaccharide biosynthesis.

Sabine Gronow1, Werner Brabetz, Buko Lindner, Helmut Brade.   

Abstract

The inner core region of the lipopolysaccharide (LPS) of Haemophilus influenzae is characterized by the presence of a phosphorylated 3-deoxy-alpha-D-manno-octulosonic acid (Kdo). In this study, we show that the heptosyltransferase I adding the first L-glycero-D-manno-heptose residue to this acceptor is encoded by the gene opsX, which differs in substrate specificity from the other heptosyltransferase I, known as WaaC.

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Year:  2005        PMID： 16109967      PMCID： PMC1196153          DOI： 10.1128/JB.187.17.6242-6247.2005

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  34 in total

1.  The structure of the carbohydrate backbone of the LPS from Shewanella putrefaciens CN32.

Authors:  Evgeny Vinogradov; Anton Korenevsky; Terry J Beveridge
Journal:  Carbohydr Res       Date:  2002-08-16       Impact factor: 2.104

2.  High rates of recombination in otitis media isolates of non-typeable Haemophilus influenzae.

Authors:  Alison J Cody; Dawn Field; Edward J Feil; Suzanna Stringer; Mary E Deadman; Anthony G Tsolaki; Brett Gratz; Valérie Bouchet; Richard Goldstein; Derek W Hood; E Richard Moxon
Journal:  Infect Genet Evol       Date:  2003-05       Impact factor: 3.342

3.  A new method for the extraction of R lipopolysaccharides.

Authors:  C Galanos; O Lüderitz; O Westphal
Journal:  Eur J Biochem       Date:  1969-06

4.  A Haemophilus influenzae gene that encodes a membrane bound 3-deoxy-D-manno-octulosonic acid (Kdo) kinase. Possible involvement of kdo phosphorylation in bacterial virulence.

Authors:  K A White; S Lin; R J Cotter; C R Raetz
Journal:  J Biol Chem       Date:  1999-10-29       Impact factor: 5.157

5.  3-Deoxy-D-manno-oct-2-ulosonic acid (Kdo) transferase (WaaA) and kdo kinase (KdkA) of Haemophilus influenzae are both required to complement a waaA knockout mutation of Escherichia coli.

Authors:  W Brabetz; S Müller-Loennies; H Brade
Journal:  J Biol Chem       Date:  2000-11-10       Impact factor: 5.157

6.  Bordetella pertussis waaA encodes a monofunctional 2-keto-3-deoxy-D-manno-octulosonic acid transferase that can complement an Escherichia coli waaA mutation.

Authors:  T Isobe; K A White; A G Allen; M Peacock; C R Raetz; D J Maskell
Journal:  J Bacteriol       Date:  1999-04       Impact factor: 3.490

7.  Cloning, sequencing, and functional analysis of three glycosyltransferases involved in the biosynthesis of the inner core region of Klebsiella pneumoniae lipopolysaccharide.

Authors:  C Noah; W Brabetz; S Gronow; H Brade
Journal:  J Endotoxin Res       Date:  2001

8.  Construction of a deep-rough mutant of Burkholderia cepacia ATCC 25416 and characterization of its chemical and biological properties.

Authors:  Sabine Gronow; Christian Noah; Antje Blumenthal; Buko Lindner; Helmut Brade
Journal:  J Biol Chem       Date:  2002-11-08       Impact factor: 5.157

9.  Influence of temperature on growth of lipopolysaccharide-deficient (rough) mutants of Salmonella typhimurium and Salmonella minnesota.

Authors:  A K Chatterjee; K E Sanderson; H Ross
Journal:  Can J Microbiol       Date:  1976-10       Impact factor: 2.419

10.  Genetic and structural characterization of the core region of the lipopolysaccharide from Serratia marcescens N28b (serovar O4).

Authors:  Núria Coderch; Núria Piqué; Buko Lindner; Nihal Abitiu; Susana Merino; Luis Izquierdo; Natalia Jimenez; Juan M Tomás; Otto Holst; Miguel Regué
Journal:  J Bacteriol       Date:  2004-02       Impact factor: 3.490
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  8 in total

1.  The modA10 phasevarion of nontypeable Haemophilus influenzae R2866 regulates multiple virulence-associated traits.

Authors:  Timothy M VanWagoner; John M Atack; Kevin L Nelson; Hannah K Smith; Kate L Fox; Michael P Jennings; Terrence L Stull; Arnold L Smith
Journal:  Microb Pathog       Date:  2015-12-21       Impact factor: 3.738

2.  Haemophilus parainfluenzae has a limited core lipopolysaccharide repertoire with no phase variation.

Authors:  Rosanna E B Young; Derek W Hood
Journal:  Glycoconj J       Date:  2012-10-24       Impact factor: 2.916

3.  Relative contributions of lipooligosaccharide inner and outer core modifications to nontypeable Haemophilus influenzae pathogenesis.

Authors:  Pau Morey; Cristina Viadas; Begoña Euba; Derek W Hood; Montserrat Barberán; Carmen Gil; María Jesús Grilló; José Antonio Bengoechea; Junkal Garmendia
Journal:  Infect Immun       Date:  2013-08-26       Impact factor: 3.441

4.  Pasteurella multocida expresses two lipopolysaccharide glycoforms simultaneously, but only a single form is required for virulence: identification of two acceptor-specific heptosyl I transferases.

Authors:  Marina Harper; John D Boyce; Andrew D Cox; Frank St Michael; Ian W Wilkie; P J Blackall; Ben Adler
Journal:  Infect Immun       Date:  2007-05-21       Impact factor: 3.441

5.  Molecular analysis of three Aeromonas hydrophila AH-3 (serotype O34) lipopolysaccharide core biosynthesis gene clusters.

Authors:  Natalia Jimenez; Rocío Canals; Anna Lacasta; Anna N Kondakova; Buko Lindner; Yuriy A Knirel; Susana Merino; Miguel Regué; Juan M Tomás
Journal:  J Bacteriol       Date:  2008-02-29       Impact factor: 3.490

6.  Tracking insertion mutants within libraries by deep sequencing and a genome-wide screen for Haemophilus genes required in the lung.

Authors:  Jeffrey D Gawronski; Sandy M S Wong; Georgia Giannoukos; Doyle V Ward; Brian J Akerley
Journal:  Proc Natl Acad Sci U S A       Date:  2009-09-04       Impact factor: 11.205

7.  Experimental identification of Actinobacillus pleuropneumoniae strains L20 and JL03 heptosyltransferases, evidence for a new heptosyltransferase signature sequence.

Authors:  Susana Merino; Yuriy A Knirel; Miguel Regué; Juan M Tomás
Journal:  PLoS One       Date:  2013-01-30       Impact factor: 3.240

8.  Two Glycosyltransferase Genes of Haemophilus parasuis SC096 Implicated in Lipooligosaccharide Biosynthesis, Serum Resistance, Adherence, and Invasion.

Authors:  Qi Zhou; Saixiang Feng; Jianmin Zhang; Aiqing Jia; Kaijie Yang; Kaixiang Xing; Ming Liao; Huiying Fan
Journal:  Front Cell Infect Microbiol       Date:  2016-09-12       Impact factor: 5.293
  8 in total

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