Literature DB >> 16109509

What does it take to bind CAR?

Lane K Law1, Beverly L Davidson.   

Abstract

Recombinant adenoviruses (Ads) have been used as reagents for biological studies and therapeutic protocols for the treatment of human patients. The two most commonly used Ads, Ad2 and Ad5, infect a broad range of tissues through interaction with the coxsackie and adenovirus receptor CAR. Both mutational analyses and crystal structure data have established residues in the fiber knob and shaft critical for Ad-CAR binding. In this report we review the contributions of various residues to Ad-CAR binding, taking into consideration the documented cellular tropism of other Ad serotypes.

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Year:  2005        PMID： 16109509     DOI： 10.1016/j.ymthe.2005.05.017

Source DB:  PubMed          Journal:  Mol Ther        ISSN： 1525-0016            Impact factor:   11.454


  24 in total

1.  The transduction of Coxsackie and Adenovirus Receptor-negative cells and protection against neutralizing antibodies by HPMA-co-oligolysine copolymer-coated adenovirus.

Authors:  Chung-Huei K Wang; Leslie W Chan; Russell N Johnson; David S H Chu; Julie Shi; Joan G Schellinger; André Lieber; Suzie H Pun
Journal:  Biomaterials       Date:  2011-09-28       Impact factor: 12.479

2.  Fiber shaft-chimeric adenovirus vectors lacking the KKTK motif efficiently infect liver cells in vivo.

Authors:  Nelson C Di Paolo; Oleksandr Kalyuzhniy; Dmitry M Shayakhmetov
Journal:  J Virol       Date:  2007-09-12       Impact factor: 5.103

Review 3.  Adenovirus.

Authors:  Jason G Smith; Christopher M Wiethoff; Phoebe L Stewart; Glen R Nemerow
Journal:  Curr Top Microbiol Immunol       Date:  2010       Impact factor: 4.291

4.  Usage of integrin and heparan sulfate as receptors for mouse adenovirus type 1.

Authors:  Sharmila Raman; Tien-Huei Hsu; Shanna L Ashley; Katherine R Spindler
Journal:  J Virol       Date:  2009-01-28       Impact factor: 5.103

5.  Mechanisms of human adenovirus inactivation by sunlight and UVC light as examined by quantitative PCR and quantitative proteomics.

Authors:  Franziska Bosshard; Florence Armand; Romain Hamelin; Tamar Kohn
Journal:  Appl Environ Microbiol       Date:  2012-12-14       Impact factor: 4.792

6.  Requirements for receptor engagement during infection by adenovirus complexed with blood coagulation factor X.

Authors:  Angela C Bradshaw; Alan L Parker; Margaret R Duffy; Lynda Coughlan; Nico van Rooijen; Veli-Matti Kähäri; Stuart A Nicklin; Andrew H Baker
Journal:  PLoS Pathog       Date:  2010-10-07       Impact factor: 6.823

7.  Integrin alphavbeta5 is a primary receptor for adenovirus in CAR-negative cells.

Authors:  Cynthia Lyle; Frank McCormick
Journal:  Virol J       Date:  2010-07-08       Impact factor: 4.099

8.  Improved adenovirus type 5 vector-mediated transduction of resistant cells by piggybacking on coxsackie B-adenovirus receptor-pseudotyped baculovirus.

Authors:  Ophélia Granio; Marine Porcherot; Stéphanie Corjon; Kuntida Kitidee; Petra Henning; Assia Eljaafari; Andrea Cimarelli; Leif Lindholm; Pierre Miossec; Pierre Boulanger; Saw-See Hong
Journal:  J Virol       Date:  2009-04-08       Impact factor: 5.103

9.  Alternate serotype adenovector provides long-term therapeutic gene expression in the eye.

Authors:  Melissa M Hamilton; Gordon A Byrnes; Jason G Gall; Douglas E Brough; C Richter King; Lisa L Wei
Journal:  Mol Vis       Date:  2008-12-30       Impact factor: 2.367

Review 10.  Adenovirus receptors and their implications in gene delivery.

Authors:  Anurag Sharma; Xiaoxin Li; Dinesh S Bangari; Suresh K Mittal
Journal:  Virus Res       Date:  2009-02-26       Impact factor: 3.303
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