Literature DB >> 16109454

Homocysteine and folate metabolism in depression.

Teodoro Bottiglieri1.   

Abstract

Homocysteine is a sensitive marker of folate and vitamin B12 deficiency. Numerous studies have confirmed the association between folate deficiency and depression. It is not completely understood whether homocysteine is solely a marker for folate deficiency or if it may play a more direct role in the expression of mood disorders. This review describes the biochemical, neurochemical and clinical correlations of folate deficiency and hyperhomocysteinemia in relation to depression.

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Year:  2005        PMID： 16109454     DOI： 10.1016/j.pnpbp.2005.06.021

Source DB:  PubMed          Journal:  Prog Neuropsychopharmacol Biol Psychiatry        ISSN： 0278-5846            Impact factor:   5.067


  57 in total

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Authors:  Bahram Pourghassem Gargari; Maryam Saboktakin; Soltanali Mahboob; Nosratollah Pourafkari
Journal:  Health Promot Perspect       Date:  2012-12-28

2.  Vitamin B12, homocysteine and depressive symptoms: a longitudinal study among older adults.

Authors:  L E M Elstgeest; I A Brouwer; B Wj H Penninx; N M van Schoor; M Visser
Journal:  Eur J Clin Nutr       Date:  2017-02-01       Impact factor: 4.016

3.  Acute mood but not cognitive improvements following administration of a single multivitamin and mineral supplement in healthy women aged 50 and above: a randomised controlled trial.

Authors:  H Macpherson; R Rowsell; K H M Cox; A Scholey; A Pipingas
Journal:  Age (Dordr)       Date:  2015-04-24

4.  Association studies of genetic scores of serum vitamin B12 and folate levels with symptoms of depression and anxiety in two danish population studies.

Authors:  L T Møllehave; T Skaaby; K S Simonsen; B H Thuesen; E L Mortensen; C H Sandholt; O Pedersen; N Grarup; T Hansen; A Linneberg
Journal:  Eur J Clin Nutr       Date:  2017-06-28       Impact factor: 4.016

Review 5.  Effect of supplementation with methyl-donor nutrients on neurodevelopment and cognition: considerations for future research.

Authors:  Sarah E McKee; Teresa M Reyes
Journal:  Nutr Rev       Date:  2018-07-01       Impact factor: 7.110

6.  The folic acid endophenotype and depression in an elderly population.

Authors:  N Naumovski; M Veysey; X Ng; L Boyd; L Dufficy; B Blades; C Travers; P Lewis; J Sturm; M Townley-Jones; Z Yates; P Roach; M Lucock
Journal:  J Nutr Health Aging       Date:  2010-12       Impact factor: 4.075

7.  The efficacy of vitamins for reducing or preventing depression symptoms in healthy individuals: natural remedy or placebo?

Authors:  Alison America; Leonard S Milling
Journal:  J Behav Med       Date:  2008-04

8.  Dependence of the geriatric depression scores on age, nutritional status, and haematologic variables in elderly institutionalized patients.

Authors:  C H Alves de Rezende; L M Coelho; L M Oliveira; N Penha Silva
Journal:  J Nutr Health Aging       Date:  2009-08       Impact factor: 4.075

9.  Folate metabolism genes, dietary folate and response to antidepressant medications in late-life depression.

Authors:  Brenda D Jamerson; Martha E Payne; Melanie E Garrett; Allison E Ashley-Koch; Marcy C Speer; David C Steffens
Journal:  Int J Geriatr Psychiatry       Date:  2012-12-20       Impact factor: 3.485

10.  The B-VITAGE trial: a randomized trial of homocysteine lowering treatment of depression in later life.

Authors:  Andrew H Ford; Leon Flicker; Kieran McCaul; Frank van Bockxmeer; Sarah Hegarty; Varsha Hirani; Stephen Fenner; Osvaldo P Almeida
Journal:  Trials       Date:  2010-01-25       Impact factor: 2.279
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