Literature DB >> 16109366

TPX or not TPX?

Eric Karsenti1.   

Abstract

An Aurora A regulatory module has been identified in two different proteins: TPX2 in Xenopus laevis and TPXL-1 in C. elegans. The diverse roles of these two proteins in spindle assembly leave us to beckon the true C. elegans TPX2 ortholog to center stage.

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Year:  2005        PMID： 16109366     DOI： 10.1016/j.molcel.2005.08.002

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  9 in total

1.  Plant TPX2 and related proteins.

Authors:  Jean-Luc Evrard; Laurent Pieuchot; Jan W Vos; Isabelle Vernos; Anne-Catherine Schmit
Journal:  Plant Signal Behav       Date:  2009-01

2.  Targeting protein for xenopus kinesin-like protein 2 (TPX2) regulates γ-histone 2AX (γ-H2AX) levels upon ionizing radiation.

Authors:  Gernot Neumayer; Angela Helfricht; Su Yeon Shim; Hoa Thi Le; Cecilia Lundin; Camille Belzil; Mathieu Chansard; Yaping Yu; Susan P Lees-Miller; Oliver J Gruss; Haico van Attikum; Thomas Helleday; Minh Dang Nguyen
Journal:  J Biol Chem       Date:  2012-10-08       Impact factor: 5.157

3.  The plant TPX2 protein regulates prospindle assembly before nuclear envelope breakdown.

Authors:  Jan W Vos; Laurent Pieuchot; Jean-Luc Evrard; Natacha Janski; Marc Bergdoll; Dryas de Ronde; Laurent H Perez; Teresa Sardon; Isabelle Vernos; Anne-Catherine Schmit
Journal:  Plant Cell       Date:  2008-10-21       Impact factor: 11.277

Review 4.  Non-centrosomal TPX2-Dependent Regulation of the Aurora A Kinase: Functional Implications for Healthy and Pathological Cell Division.

Authors:  Georgina Garrido; Isabelle Vernos
Journal:  Front Oncol       Date:  2016-04-15       Impact factor: 6.244

5.  Assembly of Caenorhabditis elegans acentrosomal spindles occurs without evident microtubule-organizing centers and requires microtubule sorting by KLP-18/kinesin-12 and MESP-1.

Authors:  Ian D Wolff; Michael V Tran; Timothy J Mullen; Anne M Villeneuve; Sarah M Wignall
Journal:  Mol Biol Cell       Date:  2016-08-24       Impact factor: 4.138

6.  The C-terminal domain of TPX2 is made of alpha-helical tandem repeats.

Authors:  Luis Sanchez-Pulido; Laurent Perez; Steffen Kuhn; Isabelle Vernos; Miguel A Andrade-Navarro
Journal:  BMC Struct Biol       Date:  2016-10-26

7.  Structural insight into TPX2-stimulated microtubule assembly.

Authors:  Rui Zhang; Johanna Roostalu; Thomas Surrey; Eva Nogales
Journal:  Elife       Date:  2017-11-09       Impact factor: 8.140

8.  Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A.

Authors:  Alexander W Bird; Anthony A Hyman
Journal:  J Cell Biol       Date:  2008-07-28       Impact factor: 10.539

9.  TPX2 levels modulate meiotic spindle size and architecture in Xenopus egg extracts.

Authors:  Kara J Helmke; Rebecca Heald
Journal:  J Cell Biol       Date:  2014-07-28       Impact factor: 10.539
  9 in total

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