Literature DB >> 1610906

Cloning and nucleotide sequences of two lipase genes from Candida cylindracea.

S Longhi1, F Fusetti, R Grandori, M Lotti, M Vanoni, L Alberghina.   

Abstract

Two lipase-encoding genes (LIP1 and LIP2) have been isolated from a SacI genomic library of the yeast Candida cylindracea and their nucleotide sequences have been determined. Comparison with the sequence of a cDNA ruled out the presence of introns in the two genes. Both ORFs encode for mature proteins of 534 residues with putative signal peptides of 15 and 14 amino acids, respectively. When compared with other lipase sequences, the two C. cylindracea lipases showed homology only with the Geotrichum candidum lipase, whereas they shared a significant similarity with several esterases.

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Year:  1992        PMID: 1610906     DOI: 10.1016/0167-4781(92)90085-e

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  11 in total

1.  Analysis of the gene family encoding lipases in Candida rugosa by competitive reverse transcription-PCR.

Authors:  G C Lee; S J Tang; K H Sun; J F Shaw
Journal:  Appl Environ Microbiol       Date:  1999-09       Impact factor: 4.792

2.  New nucleotide sequence data on the EMBL File Server.

Authors: 
Journal:  Nucleic Acids Res       Date:  1992-09-25       Impact factor: 16.971

3.  Molecular differentiation of seven Malassezia species.

Authors:  A K Gupta; Y Kohli; R C Summerbell
Journal:  J Clin Microbiol       Date:  2000-05       Impact factor: 5.948

4.  Mutants provide evidence of the importance of glycosydic chains in the activation of lipase 1 from Candida rugosa.

Authors:  S Brocca; M Persson; E Wehtje; P Adlercreutz; L Alberghina; M Lotti
Journal:  Protein Sci       Date:  2000-05       Impact factor: 6.725

5.  Induction of an extracellular esterase from Candida albicans and some of its properties.

Authors:  R Tsuboi; H Komatsuzaki; H Ogawa
Journal:  Infect Immun       Date:  1996-08       Impact factor: 3.441

6.  Multiple mutagenesis of non-universal serine codons of the Candida rugosa LIP2 gene and biochemical characterization of purified recombinant LIP2 lipase overexpressed in Pichia pastoris.

Authors:  Guan-Chiun Lee; Li-Chiun Lee; Vasyl Sava; Jei-Fu Shaw
Journal:  Biochem J       Date:  2002-09-01       Impact factor: 3.857

Review 7.  Protein engineering and applications of Candida rugosa lipase isoforms.

Authors:  Casimir C Akoh; Guan-Chiun Lee; Jei-Fu Shaw
Journal:  Lipids       Date:  2004-06       Impact factor: 1.880

8.  Contribution to the study of the alteration of lipase activity of Candida rugosa by ions and buffers.

Authors:  M J Hernáiz; M Rua; B Celda; P Medina; J V Sinisterra; J M Sánchez-Montero
Journal:  Appl Biochem Biotechnol       Date:  1994-03       Impact factor: 2.926

9.  Localization of lipase genes on Candida rugosa chromosomes.

Authors:  S Brocca; R Grandori; D Breviario; M Lotti
Journal:  Curr Genet       Date:  1995-10       Impact factor: 3.886

10.  Design, total synthesis, and functional overexpression of the Candida rugosa lip1 gene coding for a major industrial lipase.

Authors:  S Brocca; C Schmidt-Dannert; M Lotti; L Alberghina; R D Schmid
Journal:  Protein Sci       Date:  1998-06       Impact factor: 6.725

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