Literature DB >> 16107900

A sampling of Canadian practice in managing nonvariceal upper gastrointestinal bleeding before recent guideline publication: is there room for improvement?

Karen Bensoussan1, Carlo A Fallone, Alan N Barkun, Myriam Martel.   

Abstract

BACKGROUND: There are few recent published consensus guidelines regarding nonvariceal upper gastrointestinal bleeding. In 2003, the Canadian Association of Gastroenterology sponsored a set of 20 recommendations. AIM: To compare current Canadian clinical practice patterns with these most recent guidelines.
METHODS: Data obtained from the Canadian Registry of patients with Upper Gastrointestinal Bleeding and Endoscopy (RUGBE), complemented by a questionnaire sent out to the 18 participating RUGBE sites, were used to compare present practice with all 20 guidelines.
RESULTS: Only three RUGBE sites had an explicit written protocol for nonvariceal upper gastrointestinal bleeding, and only 40% of the sites had support staff available after hours. The Blatchford prognostic scale was not used routinely, and only one site used the Rockall score for risk stratification. Most patients classified as low-risk according to the literature had endoscopy within 24 h and a median length of stay of two days compared with high-risk patients who underwent endoscopy approximately 4 h earlier, had a median length of stay of 4.3 days and displayed a higher mortality. Nineteen per cent of all patients had a routine second-look endoscopy. Proton pump inhibitors were frequently used in the acute setting. Thirteen per cent of all patients rebled and only 34% of these received a second endoscopy. One-half of all patients were tested for Helicobacter pylori while in hospital, mostly by histology, and one-third of those who tested positive received H pylori eradication during their hospitalization.
CONCLUSION: Compared with recommendations put forward in the new guidelines, clinical practice before guideline publication was variable. The future level of guideline adherence and patient outcome data should be quantified and monitored as the guidelines are disseminated.

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Year:  2005        PMID: 16107900     DOI: 10.1155/2005/198387

Source DB:  PubMed          Journal:  Can J Gastroenterol        ISSN: 0835-7900            Impact factor:   3.522


  8 in total

1.  Does blood urea nitrogen level predict severity and high-risk endoscopic lesions in patients with nonvariceal upper gastrointestinal bleeding?

Authors:  Khalid Al-Naamani; Nabil Alzadjali; Alan N Barkun; Carlo A Fallone
Journal:  Can J Gastroenterol       Date:  2008-04       Impact factor: 3.522

2.  Barriers to the implementation of practice guidelines in managing patients with nonvariceal upper gastrointestinal bleeding: A qualitative approach.

Authors:  Sean M Hayes; Suzanne Murray; Martin Dupuis; Martin Dawes; Ian A Hawes; Alan N Barkun
Journal:  Can J Gastroenterol       Date:  2010-05       Impact factor: 3.522

3.  Adherence to guidelines: a national audit of the management of acute upper gastrointestinal bleeding. The REASON registry.

Authors:  Yidan Lu; Alan N Barkun; Myriam Martel
Journal:  Can J Gastroenterol Hepatol       Date:  2014-10

4.  Effectiveness of disseminating consensus management recommendations for ulcer bleeding: a cluster randomized trial.

Authors:  Alan N Barkun; Mamatha Bhat; David Armstrong; Martin Dawes; Allan Donner; Robert Enns; Janet Martin; Paul Moayyedi; Joseph Romagnuolo; Larry Stitt
Journal:  CMAJ       Date:  2013-01-14       Impact factor: 8.262

5.  Predictors of early rebleeding after endoscopic therapy in patients with nonvariceal upper gastrointestinal bleeding secondary to high-risk lesions.

Authors:  Davide Maggio; Alan N Barkun; Myriam Martel; Sara Elouali; Ian M Gralnek
Journal:  Can J Gastroenterol       Date:  2013-08       Impact factor: 3.522

6.  Peptic ulcer diseases: genetics, mechanism, and therapies.

Authors:  Seng-Kee Chuah; Deng-Chyang Wu; Hidekazu Suzuki; Khean-Lee Goh; John Kao; Jian-Lin Ren
Journal:  Biomed Res Int       Date:  2014-12-28       Impact factor: 3.411

7.  Consensus on control of risky nonvariceal upper gastrointestinal bleeding in Taiwan with National Health Insurance.

Authors:  Bor-Shyang Sheu; Chun-Ying Wu; Ming-Shiang Wu; Cheng-Tang Chiu; Chun-Che Lin; Ping-I Hsu; Hsiu-Chi Cheng; Teng-Yu Lee; Hsiu-Po Wang; Jaw-Town Lin
Journal:  Biomed Res Int       Date:  2014-08-14       Impact factor: 3.411

8.  Glasgow Blatchford Score of limited benefit for low-risk urban patients: a mixed methods study.

Authors:  David A Leiman; Angela M Mills; Frances S Shofer; Andrew T Weber; Erin R Leiman; Brian P Riff; James D Lewis; Shivan J Mehta
Journal:  Endosc Int Open       Date:  2017-09-29
  8 in total

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