| Literature DB >> 16106060 |
Winfried Barchet1, Amanda Blasius, Marina Cella, Marco Colonna.
Abstract
Plasmacytoid dendritic cells (pDCs) have been associated with several names and functions over time, reflecting the limited availability of specific markers and their ability to produce large amounts of type I interferons, present antigens, as well as prime disparate T-cell helper responses. Yet, there is increasing evidence that pDCs are a distinct cell type in the innate immune system. This review highlights aspects in which pDCs are unique in comparison to other antigen-presenting cells in regulating innate and adaptive immune responses.Mesh:
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Year: 2005 PMID: 16106060 DOI: 10.1385/IR:32:1-3:075
Source DB: PubMed Journal: Immunol Res ISSN: 0257-277X Impact factor: 2.829