| Literature DB >> 16105737 |
Chandan Singh1, Heetika Malik, Sunil K Puri.
Abstract
A new series of functionalized 1,2,4-trioxanes 10-21 have been prepared and assessed for antimalarial activity in mice. Several of these trioxanes show significant activity. Trioxane 16, the most active compound of the series, has shown activity by oral route which is comparable with that of the clinically used drug, beta-arteether.Entities:
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Year: 2005 PMID： 16105737 DOI： 10.1016/j.bmcl.2005.07.013
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823