Literature DB >> 16105229

Cytotoxic activity and effect on nitric oxide production of tirucallane-type triterpenes.

Ibeth Oviedo Chávez1, Teresa Ramírez Apan, Mariano Martínez-Vázquez.   

Abstract

Hexane extract from the bark of Amphipterygium adstringens, as well as its principal constituents, masticadienonic acid and 3alpha-hydroxymasticadienolic acid, inhibited the growth of five human cancer cell lines. Derivatives of, namely 24,25 S-dihydromasticadienonic acid and masticadienolic acid, were also evaluated. The results showed that both and had greater activity than on colon cancer cell lines. The effects of on the production of nitric oxide (NO) from both resting and lipopolysaccharide-activated macrophages were determined. It was found that and caused an increase in NO release from resting macrophages; in lipopolysaccharide-activated macrophages, only and caused an increase in NO production.

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Year:  2005        PMID： 16105229     DOI： 10.1211/jpp.57.9.0003

Source DB:  PubMed          Journal:  J Pharm Pharmacol        ISSN： 0022-3573            Impact factor:   3.765


  8 in total

Review 1.  Triterpenoids as potential agents for the chemoprevention and therapy of breast cancer.

Authors:  Anupam Bishayee; Shamima Ahmed; Nikoleta Brankov; Marjorie Perloff
Journal:  Front Biosci (Landmark Ed)       Date:  2011-01-01

2.  Protective Effect of Amphipterygium adstringens Extract on Dextran Sulphate Sodium-Induced Ulcerative Colitis in Mice.

Authors:  Mario Rodriguez-Canales; Ruben Jimenez-Rivas; Maria Margarita Canales-Martinez; Ana Judith Garcia-Lopez; Nelly Rivera-Yañez; Oscar Nieto-Yañez; Yadira Ledesma-Soto; Luvia Enid Sanchez-Torres; Miriam Rodriguez-Sosa; Luis Ignacio Terrazas; Marco Aurelio Rodriguez-Monroy
Journal:  Mediators Inflamm       Date:  2016-08-21       Impact factor: 4.711

3.  Masticadienonic and 3α-OH Masticadienoic Acids Induce Apoptosis and Inhibit Cell Proliferation and Tumor Growth in Prostate Cancer Xenografts in Vivo.

Authors:  Ma Beatriz Sánchez-Monroy; Nadia J Jacobo-Herrera; Alejandro Zentella-Dehesa; Beatriz Hernández-Téllez; Mariano Martínez-Vázquez
Journal:  Molecules       Date:  2017-09-06       Impact factor: 4.411

Review 4.  Natural Compounds in Sex Hormone-Dependent Cancers: The Role of Triterpenes as Therapeutic Agents.

Authors:  Codruţa Şoica; Mirela Voicu; Roxana Ghiulai; Cristina Dehelean; Roxana Racoviceanu; Cristina Trandafirescu; Oana-Janina Roșca; Gabriela Nistor; Marius Mioc; Alexandra Mioc
Journal:  Front Endocrinol (Lausanne)       Date:  2021-01-21       Impact factor: 5.555

5.  Immunomodulatory Properties of Masticadienonic Acid and 3α-Hydroxy Masticadienoic Acid in Dendritic Cells.

Authors:  Gabriela Piñón-Zárate; Fernanda Reyes-Riquelme; Ma Beatriz Sánchez-Monroy; Mónica Velasco-Torrez; Mariano Martínez-Vázquez; Christian Adrian Cárdenas-Monroy; Beatriz Hernandez-Téllez; Katia Jarquín-Yáñez; Miguel Ángel Herrera-Enríquez; Andrés Eliú Castell-Rodríguez
Journal:  Molecules       Date:  2022-02-21       Impact factor: 4.411

6.  In Vitro Antimicrobial and Antiproliferative Activity of Amphipterygium adstringens.

Authors:  A Rodriguez-Garcia; I T A Peixoto; M J Verde-Star; S De la Torre-Zavala; H Aviles-Arnaut; A L T G Ruiz
Journal:  Evid Based Complement Alternat Med       Date:  2015-09-14       Impact factor: 2.629

Review 7.  Medicinal Plants from Mexico, Central America, and the Caribbean Used as Immunostimulants.

Authors:  Angel Josabad Alonso-Castro; María Del Carmen Juárez-Vázquez; Nimsi Campos-Xolalpa
Journal:  Evid Based Complement Alternat Med       Date:  2016-03-03       Impact factor: 2.629

Review 8.  Structure-Based Classification and Anti-Cancer Effects of Plant Metabolites.

Authors:  Seong-Ah Shin; Sun Young Moon; Woe-Yeon Kim; Seung-Mann Paek; Hyun Ho Park; Chang Sup Lee
Journal:  Int J Mol Sci       Date:  2018-09-06       Impact factor: 5.923
  8 in total

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