Literature DB >> 16105126

No correlation between clinical symptoms and Blastocystis hominis in immunocompetent individuals.

Karin Leder1, Margaret E Hellard, Martha I Sinclair, Christopher K Fairley, Rory Wolfe.   

Abstract

UNLABELLED: Abstract Background and Aim: Previous reports regarding the clinical significance and pathogenicity of Blastocystis hominis have been contradictory. The aim of this study was to examine the association between Blastocystis and gastrointestinal symptoms in immunocompetent individuals.
METHODS: We monitored over 2800 healthy people for a period of 15 months, and took stool specimens during both asymptomatic periods and during periods of gastrointestinal symptoms.
RESULTS: After exclusion of individuals who had simultaneous identification of other fecal pathogens, we compared the proportions of asymptomatic versus symptomatic individuals positive for Blastocystis and found no significant difference (P = 0.5). Symptom status did not correlate with parasite abundance. We found that some individuals were likely to have Blastocystis detected during both asymptomatic and symptomatic periods, possibly suggesting carriage of the organism.
CONCLUSION: In conclusion, we found no correlation between clinical symptoms and the presence or absence of Blastocystis among this healthy cohort. Copyright 2005 Blackwell Publishing Asia Pty Ltd.

Entities:  

Mesh:

Year:  2005        PMID: 16105126     DOI: 10.1111/j.1440-1746.2005.03868.x

Source DB:  PubMed          Journal:  J Gastroenterol Hepatol        ISSN: 0815-9319            Impact factor:   4.029


  29 in total

1.  Proteaese activity of Blastocystis hominis subtype3 in symptomatic and asymptomatic patients.

Authors:  Dina Marie Abdel-Hameed; Omayma Mohamed Hassanin
Journal:  Parasitol Res       Date:  2011-01-29       Impact factor: 2.289

2.  Immunopathological assessments of human Blastocystis spp. in experimentally infected immunocompetent and immunosuppresed mice.

Authors:  Ekhlas H Abdel-Hafeez; Azza K Ahmad; Noha H Abdelgelil; Manal Z M Abdellatif; Amany M Kamal; Kamel M A Hassanin; Abdel-Razik H Abdel-Razik; Ehab M Abdel-Raheem
Journal:  Parasitol Res       Date:  2016-02-10       Impact factor: 2.289

3.  Blastocystis ratti induces contact-independent apoptosis, F-actin rearrangement, and barrier function disruption in IEC-6 cells.

Authors:  Manoj K Puthia; Selena W S Sio; Jia Lu; Kevin S W Tan
Journal:  Infect Immun       Date:  2006-07       Impact factor: 3.441

4.  Prevalence and Clinical Features of Blastocystis hominis Infection among Patients in Sebha, Libya.

Authors:  Mohammed A Al-Fellani; Abdul H Khan; Rugaia M Al-Gazoui; Mabrouk K Zaid; Mahmoud A Al-Ferjani
Journal:  Sultan Qaboos Univ Med J       Date:  2007-04

5.  Antiprotozoal potential of Salvadora persica against three virulent subtypes of Blastocystis sp.

Authors:  Mohammed A El-Bali; Abdulhafid Abdulhakim; Raafat T Mohamed; Mohamed A El-Malky; Rowaida A Bakri; Saeed A Al-Harthi
Journal:  J Parasit Dis       Date:  2020-07-27

6.  Development and evaluation of a real-time PCR assay for detection and quantification of blastocystis parasites in human stool samples: prospective study of patients with hematological malignancies.

Authors:  Philippe Poirier; Ivan Wawrzyniak; Aurélie Albert; Hicham El Alaoui; Frédéric Delbac; Valérie Livrelli
Journal:  J Clin Microbiol       Date:  2010-12-22       Impact factor: 5.948

Review 7.  New insights on classification, identification, and clinical relevance of Blastocystis spp.

Authors:  Kevin S W Tan
Journal:  Clin Microbiol Rev       Date:  2008-10       Impact factor: 26.132

8.  Predominance of subtype 3 among Blastocystis isolates from a major hospital in Singapore.

Authors:  Kenneth H S Wong; G C Ng; Raymond T P Lin; H Yoshikawa; Mark B Taylor; Kevin S W Tan
Journal:  Parasitol Res       Date:  2007-12-07       Impact factor: 2.289

Review 9.  Clinical significance of enteric protozoa in the immunosuppressed human population.

Authors:  D Stark; J L N Barratt; S van Hal; D Marriott; J Harkness; J T Ellis
Journal:  Clin Microbiol Rev       Date:  2009-10       Impact factor: 26.132

10.  Oh my aching gut: irritable bowel syndrome, Blastocystis, and asymptomatic infection.

Authors:  Kenneth F Boorom; Huw Smith; Laila Nimri; Eric Viscogliosi; Gregory Spanakos; Unaiza Parkar; Lan-Hua Li; Xiao-Nong Zhou; Ulgen Z Ok; Saovanee Leelayoova; Morris S Jones
Journal:  Parasit Vectors       Date:  2008-10-21       Impact factor: 3.876

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