Elsa L Segura1, Alejandro Escobar-Mesa. 1. Departamento de Microbiología y Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México, México, DF, México.
Abstract
OBJECTIVE: To assess the seroprevalence, household risk factors, and entomological indicators, in order to frame control measures in 11 Sanitary Jurisdictions of the state. MATERIAL AND METHODS: This study included 281 towns, 2 526 households, and 9782 individuals. Data were collected using a questionnaire. Blood was obtained in filter paper and a search for triatomines was conducted inside of and around dwellings. Prevalence rates were used to quantify exposure to risk factors and seropositivity. Odds ratios with 95% confidence intervals and Mantel-Haenszel chi-squared tests were obtained. Multivariate analysis was performed with unconditional logistic regression,variables included in the model were those that had a p-value up to 0.20 in the bivariate analysis. The etiologic fraction in the exposed was also obtained. RESULTS: The prevalence of Chagas disease was between 0 and 2.8%. Jurisdictions at a higher risk wereTuxpan, Panuco and Cordoba; Orizaba showed no risk. The main household risk factors were palma/zacate (palm-tree, grass leaves) roof and walls, dirt floor, the presence of the vector, and ventilation. CONCLUSIONS: Epidemiological surveillance should emphasize health education, housing improvement, and use of insecticides.
OBJECTIVE: To assess the seroprevalence, household risk factors, and entomological indicators, in order to frame control measures in 11 Sanitary Jurisdictions of the state. MATERIAL AND METHODS: This study included 281 towns, 2 526 households, and 9782 individuals. Data were collected using a questionnaire. Blood was obtained in filter paper and a search for triatomines was conducted inside of and around dwellings. Prevalence rates were used to quantify exposure to risk factors and seropositivity. Odds ratios with 95% confidence intervals and Mantel-Haenszel chi-squared tests were obtained. Multivariate analysis was performed with unconditional logistic regression,variables included in the model were those that had a p-value up to 0.20 in the bivariate analysis. The etiologic fraction in the exposed was also obtained. RESULTS: The prevalence of Chagas disease was between 0 and 2.8%. Jurisdictions at a higher risk wereTuxpan, Panuco and Cordoba; Orizaba showed no risk. The main household risk factors were palma/zacate (palm-tree, grass leaves) roof and walls, dirt floor, the presence of the vector, and ventilation. CONCLUSIONS: Epidemiological surveillance should emphasize health education, housing improvement, and use of insecticides.
Authors: Angel Ramos-Ligonio; Aracely López-Monteon; Daniel Guzmán-Gómez; José Luis Rosales-Encina; Yairh Limón-Flores; Eric Dumonteil Journal: Am J Trop Med Hyg Date: 2010-07 Impact factor: 2.345