Literature DB >> 1610410

Prevention of binding of rgp120 by anti-HIV active tannins.

J L Weaver1, P S Pine, G Dutschman, Y C Cheng, K H Lee, A Aszalos.   

Abstract

Several tannins with anti-HIV activity have been described previously (Nonaka et al., J Nat Prod 53: 587-595, 1990). We have shown that the tannins chebulinic acid and punicalin were able to block the binding of HIV rgp120 to CD4. These compounds were not toxic to stimulated human peripheral blood lymphocytes at concentrations ten times above their maximal effective concentration.

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Year:  1992        PMID： 1610410     DOI： 10.1016/0006-2952(92)90328-g

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN： 0006-2952            Impact factor:   5.858


  3 in total

Review 1.  Antiviral therapy for human immunodeficiency virus infections.

Authors:  E De Clercq
Journal:  Clin Microbiol Rev       Date:  1995-04       Impact factor: 26.132

2.  Hydrolyzable tannins (chebulagic acid and punicalagin) target viral glycoprotein-glycosaminoglycan interactions to inhibit herpes simplex virus 1 entry and cell-to-cell spread.

Authors:  Liang-Tzung Lin; Ting-Ying Chen; Chueh-Yao Chung; Ryan S Noyce; T Bruce Grindley; Craig McCormick; Ta-Chen Lin; Guey-Horng Wang; Chun-Ching Lin; Christopher D Richardson
Journal:  J Virol       Date:  2011-02-09       Impact factor: 5.103

3.  Geraniin extracted from the rind of Nephelium lappaceum binds to dengue virus type-2 envelope protein and inhibits early stage of virus replication.

Authors:  Siti Aisyah Abdul Ahmad; Uma D Palanisamy; Bimo A Tejo; Miaw Fang Chew; Hong Wai Tham; Sharifah Syed Hassan
Journal:  Virol J       Date:  2017-11-21       Impact factor: 4.099
  3 in total

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