| Literature DB >> 1610345 |
A Chopra1, D L Ferreira-Alves, P Sirois, J P Thirion.
Abstract
The guinea pig 5-lipoxygenase (5-LO) gene and its promoter were cloned from a guinea pig genomic DNA library. Sequencing analysis of the guinea pig promoter revealed that expression of the 5-LO gene in this rodent is probably governed by cis acting nucleotide sequences quite similar to the human gene. Nucleotide sequences that bind factors like Sp-1, AP-2, NF-kB and c-Ha-ras were identified in the guinea pig 5-LO promoter region.Entities:
Mesh:
Substances:
Year: 1992 PMID: 1610345 DOI: 10.1016/0006-291x(92)91651-6
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN: 0006-291X Impact factor: 3.575