Literature DB >> 1610345

Cloning of the guinea pig 5-lipoxygenase gene and nucleotide sequence of its promoter.

A Chopra1, D L Ferreira-Alves, P Sirois, J P Thirion.   

Abstract

The guinea pig 5-lipoxygenase (5-LO) gene and its promoter were cloned from a guinea pig genomic DNA library. Sequencing analysis of the guinea pig promoter revealed that expression of the 5-LO gene in this rodent is probably governed by cis acting nucleotide sequences quite similar to the human gene. Nucleotide sequences that bind factors like Sp-1, AP-2, NF-kB and c-Ha-ras were identified in the guinea pig 5-LO promoter region.

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Year:  1992        PMID: 1610345     DOI: 10.1016/0006-291x(92)91651-6

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  4 in total

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Authors:  Michael J Morgan; Zheng-gang Liu
Journal:  Cell Res       Date:  2010-12-28       Impact factor: 25.617

2.  Electrophilic fatty acid species inhibit 5-lipoxygenase and attenuate sepsis-induced pulmonary inflammation.

Authors:  Khader Awwad; Svenja D Steinbrink; Timo Frömel; Nicole Lill; Johann Isaak; Ann-Kathrin Häfner; Jessica Roos; Bettina Hofmann; Heinrich Heide; Gerd Geisslinger; Dieter Steinhilber; Bruce A Freeman; Thorsten J Maier; Ingrid Fleming
Journal:  Antioxid Redox Signal       Date:  2014-02-03       Impact factor: 8.401

Review 3.  NF-kB as a key player in regulation of cellular radiation responses and identification of radiation countermeasures.

Authors:  Vijay Singh; Damodar Gupta; Rajesh Arora
Journal:  Discoveries (Craiova)       Date:  2015-03-31

4.  Recombinant human alpha fetoprotein synergistically potentiates the anti-cancer effects of 1'-S-1'-acetoxychavicol acetate when used as a complex against human tumours harbouring AFP-receptors.

Authors:  Norhafiza M Arshad; Lionel L A In; Tchen Lin Soh; Mohamad Nurul Azmi; Halijah Ibrahim; Khalijah Awang; Elena Dudich; Eduard Tatulov; Noor Hasima Nagoor
Journal:  Oncotarget       Date:  2015-06-30
  4 in total

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