Literature DB >> 16102093

Is APC activation of endothelial cell PAR1 important in severe sepsis?: No.

C T Esmon1.   

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Year:  2005        PMID： 16102093     DOI： 10.1111/j.1538-7836.2005.01573.x

Source DB:  PubMed          Journal:  J Thromb Haemost        ISSN： 1538-7836            Impact factor:   5.824


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  12 in total

1.  Roles of protease-activated receptors in a mouse model of endotoxemia.

Authors:  Eric Camerer; Ivo Cornelissen; Hiroshi Kataoka; Daniel N Duong; Yao-Wu Zheng; Shaun R Coughlin
Journal:  Blood       Date:  2006-01-24       Impact factor: 22.113

2.  Critical role of activated protein C in early coagulopathy and later organ failure, infection and death in trauma patients.

Authors:  Mitchell Jay Cohen; Mariah Call; Mary Nelson; Carolyn S Calfee; Charles T Esmon; Karim Brohi; Jean Francois Pittet
Journal:  Ann Surg       Date:  2012-02       Impact factor: 12.969

3.  Thrombin-activatable procarboxypeptidase B regulates activated complement C5a in vivo.

Authors:  Toshihiko Nishimura; Timothy Myles; Adrian M Piliponsky; Adrian M Piliposky; Peter N Kao; Gerald J Berry; Lawrence L K Leung
Journal:  Blood       Date:  2006-11-14       Impact factor: 22.113

Review 4.  The occupancy of endothelial protein C receptor by its ligand modulates the par-1 dependent signaling specificity of coagulation proteases.

Authors:  Alireza R Rezaie
Journal:  IUBMB Life       Date:  2011-03-24       Impact factor: 3.885

5.  The ligand occupancy of endothelial protein C receptor switches the protease-activated receptor 1-dependent signaling specificity of thrombin from a permeability-enhancing to a barrier-protective response in endothelial cells.

Authors:  Jong-Sup Bae; Likui Yang; Chandrashekhara Manithody; Alireza R Rezaie
Journal:  Blood       Date:  2007-09-06       Impact factor: 22.113

6.  Thrombin inhibits nuclear factor kappaB and RhoA pathways in cytokine-stimulated vascular endothelial cells when EPCR is occupied by protein C.

Authors:  Jong-Sup Bae; Alireza R Rezaie
Journal:  Thromb Haemost       Date:  2009-03       Impact factor: 5.249

Review 7.  Activated protein C in sepsis: the promise of nonanticoagulant activated protein C.

Authors:  Hartmut Weiler; Wolfram Ruf
Journal:  Curr Opin Hematol       Date:  2008-09       Impact factor: 3.284

8.  Distinct functions of activated protein C differentially attenuate acute kidney injury.

Authors:  Akanksha Gupta; Bruce Gerlitz; Mark A Richardson; Christopher Bull; David T Berg; Samreen Syed; Elizabeth J Galbreath; Barbara A Swanson; Bryan E Jones; Brian W Grinnell
Journal:  J Am Soc Nephrol       Date:  2008-12-17       Impact factor: 10.121

9.  Protease activated receptor 1 (PAR-1) activation by thrombin is protective in human pulmonary artery endothelial cells if endothelial protein C receptor is occupied by its natural ligand.

Authors:  Jong-Sup Bae; Alireza R Rezaie
Journal:  Thromb Haemost       Date:  2008-07       Impact factor: 5.249

10.  Growing insights into the potential benefits and risks of activated protein C administration in sepsis: a review of preclinical and clinical studies.

Authors:  Laith Altaweel; Daniel Sweeney; Xizhong Cui; Amisha Barochia; Charles Natanson; Peter Q Eichacker
Journal:  Biologics       Date:  2009-09-15
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