| Literature DB >> 16101411 |
Valerie Vivat-Hannah1, F Christopher Zusi.
Abstract
Retinoids have shown beneficial therapeutic effects in pre-clinical and animal models for multiple pathologic indications, however severe adverse effects, restricting dosage and efficacy of oral formulations limit their use in patients. The focus of this review includes the actual medicinal use of retinoids and chemical efforts to generate highly selective and less toxic synthetic retinoids.Entities:
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Year: 2005 PMID： 16101411 DOI： 10.2174/1389557054553820
Source DB: PubMed Journal: Mini Rev Med Chem ISSN： 1389-5575 Impact factor: 3.862