Literature DB >> 16100329

Practical management of patients with painful diabetic neuropathy.

Cynthia F Corbett1.   

Abstract

PURPOSE: Painful diabetic neuropathy (PDN) has a significant impact on patients' quality of life, affecting sleep, mood, mobility, ability to work, interpersonal relationships, overall self-worth, and independence. The purpose of this article is to provide diabetes educators with current and essential tools for PDN assessment and management.
METHODS: Medline and CINAHL database searches identified publications on the assessment and treatment of PDN. Identified research was evaluated, and information pertinent to diabetes educators was summarized.
RESULTS: Recent advancements in assessment of neuropathic pain include identifying characteristics that distinguish between neuropathic and nonneuropathic pain. In the absence of treatment, research demonstrates that nerve damage may progress while pain diminishes. Many disease-modifying and symptom-management treatment options are available.
CONCLUSION: Good glycemic control is the first priority for both prevention and management of PDN. However, even with good glycemic control, up to 20% of patients will develop PDN. PDN recognition and assessment are critical to optimize management. Although several treatment modalities are available, few patients obtain complete pain relief. Recent advances in understanding the mechanisms underlying neuropathic pain should lead to better treatment and patient outcomes. Combination therapy, including nonpharmacologic modalities, may be required. Research evaluating the efficacy of combination therapy is needed.

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Year:  2005        PMID: 16100329     DOI: 10.1177/0145721705278800

Source DB:  PubMed          Journal:  Diabetes Educ        ISSN: 0145-7217            Impact factor:   2.140


  3 in total

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Journal:  Clin J Oncol Nurs       Date:  2013-04       Impact factor: 1.027

2.  Potential for Cell-Transplant Therapy with Human Neuronal Precursors to Treat Neuropathic Pain in Models of PNS and CNS Injury: Comparison of hNT2.17 and hNT2.19 Cell Lines.

Authors:  Mary J Eaton; Yerko Berrocal; Stacey Q Wolfe
Journal:  Pain Res Treat       Date:  2012-04-24

3.  Electroacupuncture Zusanli (ST36) on Release of Nitric Oxide in the Gracile Nucleus and Improvement of Sensory Neuropathies in Zucker Diabetic Fatty Rats.

Authors:  Pei-Jing Rong; Sheng-Xing Ma
Journal:  Evid Based Complement Alternat Med       Date:  2011-06-08       Impact factor: 2.629

  3 in total

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