| Literature DB >> 16099605 |
Iain Anderson1, Alexei Sorokin, Vinayak Kapatral, Gary Reznik, Anamitra Bhattacharya, Natalia Mikhailova, Henry Burd, Victor Joukov, Denis Kaznadzey, Theresa Walunas, Niels Larsen, Gordon Pusch, Konstantinos Liolios, Yuri Grechkin, Alla Lapidus, Eugene Goltsman, Lien Chu, Michael Fonstein, S Dusko Ehrlich, Ross Overbeek, Nikos Kyrpides, Natalia Ivanova.
Abstract
Genome features of the Bacillus cereus group genomes (representative strains of Bacillus cereus, Bacillus anthracis and Bacillus thuringiensis sub spp. israelensis) were analyzed and compared with the Bacillus subtilis genome. A core set of 1381 protein families among the four Bacillus genomes, with an additional set of 933 families common to the B. cereus group, was identified. Differences in signal transduction pathways, membrane transporters, cell surface structures, cell wall, and S-layer proteins suggesting differences in their phenotype were identified. The B. cereus group has signal transduction systems including a tyrosine kinase related to two-component system histidine kinases from B. subtilis. A model for regulation of the stress responsive sigma factor sigmaB in the B. cereus group different from the well studied regulation in B. subtilis has been proposed. Despite a high degree of chromosomal synteny among these genomes, significant differences in cell wall and spore coat proteins that contribute to the survival and adaptation in specific hosts has been identified.Entities:
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Year: 2005 PMID： 16099605 DOI： 10.1016/j.femsle.2005.07.008
Source DB: PubMed Journal: FEMS Microbiol Lett ISSN： 0378-1097 Impact factor: 2.742