Literature DB >> 16096050

Splicing misplaced.

Eran Meshorer1, Tom Misteli.   

Abstract

Newly synthesized transcripts are usually spliced during transcription or immediately thereafter. So pre-mRNA splicing has been presumed to occur exclusively in the cell nucleus. In this issue of Cell, Denis et al. (2005) now report the presence of functional spliceosomes and signal-dependent pre-mRNA splicing in the cytoplasm of platelets.

Mesh：

Substances：

Year:  2005        PMID： 16096050     DOI： 10.1016/j.cell.2005.07.016

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  8 in total

Review 1.  Signal-dependent protein synthesis by activated platelets: new pathways to altered phenotype and function.

Authors:  Guy A Zimmerman; Andrew S Weyrich
Journal:  Arterioscler Thromb Vasc Biol       Date:  2008-03       Impact factor: 8.311

Review 2.  Platelets: versatile effector cells in hemostasis, inflammation, and the immune continuum.

Authors:  Adriana Vieira-de-Abreu; Robert A Campbell; Andrew S Weyrich; Guy A Zimmerman
Journal:  Semin Immunopathol       Date:  2011-08-06       Impact factor: 9.623

Review 3.  Platelet mRNA: the meaning behind the message.

Authors:  Jesse W Rowley; Hansjörg Schwertz; Andrew S Weyrich
Journal:  Curr Opin Hematol       Date:  2012-09       Impact factor: 3.284

Review 4.  Platelets in Pulmonary Immune Responses and Inflammatory Lung Diseases.

Authors:  Elizabeth A Middleton; Andrew S Weyrich; Guy A Zimmerman
Journal:  Physiol Rev       Date:  2016-08-03       Impact factor: 37.312

5.  The septic milieu triggers expression of spliced tissue factor mRNA in human platelets.

Authors:  M T Rondina; H Schwertz; E S Harris; B F Kraemer; R A Campbell; N Mackman; C K Grissom; A S Weyrich; G A Zimmerman
Journal:  J Thromb Haemost       Date:  2011-04       Impact factor: 5.824

Review 6.  Platelets as cellular effectors of inflammation in vascular diseases.

Authors:  Matthew T Rondina; Andrew S Weyrich; Guy A Zimmerman
Journal:  Circ Res       Date:  2013-05-24       Impact factor: 17.367

7.  Signal-dependent splicing of tissue factor pre-mRNA modulates the thrombogenicity of human platelets.

Authors:  Hansjörg Schwertz; Neal D Tolley; Jason M Foulks; Melvin M Denis; Ben W Risenmay; Michael Buerke; Rachel E Tilley; Matthew T Rondina; Estelle M Harris; Larry W Kraiss; Nigel Mackman; Guy A Zimmerman; Andrew S Weyrich
Journal:  J Exp Med       Date:  2006-10-23       Impact factor: 14.307

8.  Splicing of platelet resident pre-mRNAs upon activation by physiological stimuli results in functionally relevant proteome modifications.

Authors:  Giovanni Nassa; Giorgio Giurato; Giovanni Cimmino; Francesca Rizzo; Maria Ravo; Annamaria Salvati; Tuula A Nyman; Yafeng Zhu; Mattias Vesterlund; Janne Lehtiö; Paolo Golino; Alessandro Weisz; Roberta Tarallo
Journal:  Sci Rep       Date:  2018-01-11       Impact factor: 4.379
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.