| Literature DB >> 16095322 |
Matthew M Zhao1, Chuanxing Qu, Joseph E Lynch.
Abstract
A novel high-yielding Zn/CuI-mediated coupling method of alkyl halides with vinyl sulfones, vinyl sulfonates, and vinyl sulfonamides is described. This protocol is applicable for primary, secondary, and tertiary alkyl iodides and bromides. Alkyl chlorides and aryl and vinyl halides were unreactive under the reaction conditions. Formamide was found to be a superior solvent for obtaining high yields.Entities:
Mesh：
Substances：
Year: 2005 PMID： 16095322 DOI： 10.1021/jo050500g
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354