Literature DB >> 16095321

Stannous chloride in alcohol: a one-pot conversion of 2-nitro-N-arylbenzamides to 2,3-dihydro-1H-quinazoline-4-ones.

Choong Leol Yoo1, James C Fettinger, Mark J Kurth.   

Abstract

A novel one-step synthesis of 2,3-dihydro-1H-quinazolin-4-ones from 2-nitrobenzamides is reported. These reactions are mediated by stannous chloride in 0.02 M methanolic or ethanolic HCl solution and proceed in good yields.

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Year:  2005        PMID： 16095321     DOI： 10.1021/jo050450f

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  7 in total

Review 1.  2,3-Dihydroquinazolin-4(1H)-one as a privileged scaffold in drug design.

Authors:  Mariateresa Badolato; Francesca Aiello; Nouri Neamati
Journal:  RSC Adv       Date:  2018-06-07       Impact factor: 4.036

2.  N-Butyl-4-chloro-benzamide.

Authors:  Aamer Saeed; Rasheed Ahmad Khera; Naeem Abbas; Jim Simpson; Roderick G Stanley
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-11-13

3.  4-Chloro-N-m-tolyl-benzamide.

Authors:  Aamer Saeed; Madiha Irfan; Michael Bolte
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-05-20

4.  2-Fluoro-N-(4-methoxy-phen-yl)benzamide.

Authors:  Aamer Saeed; Rasheed Ahmad Khera; Madiah Arfan; Jim Simpson; Roderick G Stanley
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-03-19

5.  Potent s-cis-locked bithiazole correctors of DeltaF508 cystic fibrosis transmembrane conductance regulator cellular processing for cystic fibrosis therapy.

Authors:  Gui Jun Yu; Choong L Yoo; Baoxue Yang; Michael W Lodewyk; Liping Meng; Tamer T El-Idreesy; James C Fettinger; Dean J Tantillo; A S Verkman; Mark J Kurth
Journal:  J Med Chem       Date:  2008-09-13       Impact factor: 7.446

6.  β-Cyclodextrin: a supramolecular catalyst for metal-free approach towards the synthesis of 2-amino-4,6-diphenylnicotinonitriles and 2,3-dihydroquinazolin-4(1H)-one.

Authors:  Bijeta Mitra; Gyan Chandra Pariyar; Pranab Ghosh
Journal:  RSC Adv       Date:  2021-01-05       Impact factor: 3.361

7.  A Simple, Efficient, and Eco-Friendly Method for the Preparation of 3-Substituted-2,3-dihydroquinazolin-4(1H)-one Derivatives.

Authors:  Zainab Almarhoon; Kholood A Dahlous; Rakia Abd Alhameed; Hazem A Ghabbour; Ayman El-Faham
Journal:  Molecules       Date:  2019-11-09       Impact factor: 4.411
  7 in total

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