Literature DB >> 16095315

An improved synthesis of Fmoc-N-methyl-alpha-amino acids.

Suode Zhang1, Thavendran Govender, Thomas Norström, Per I Arvidsson.   

Abstract

A highly efficient and environmentally more benign synthesis of Fmoc-N-methyl-alpha-amino acids from the corresponding Fmoc-amino acid, via intermediate 5-oxazolidinones, has been developed by using Lewis acid catalysis for the reductive opening of the oxazolidinone ring.

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Year:  2005        PMID: 16095315     DOI: 10.1021/jo050916u

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  6 in total

1.  Optimization of RGD-Containing Cyclic Peptides against αvβ3 Integrin.

Authors:  Yan Wang; Wenwu Xiao; Yonghong Zhang; Leah Meza; Harry Tseng; Yoshikazu Takada; James B Ames; Kit S Lam
Journal:  Mol Cancer Ther       Date:  2015-12-30       Impact factor: 6.261

Review 2.  The oxazolomycin family: a review of current knowledge.

Authors:  Patrik Oleksak; Jozef Gonda; Eugenie Nepovimova; Kamil Kuca; Kamil Musilek
Journal:  RSC Adv       Date:  2020-11-09       Impact factor: 4.036

3.  Design and Synthesis of Analogues of Marine Natural Product Galaxamide, an N-methylated Cyclic Pentapeptide, as Potential Anti-Tumor Agent in Vitro.

Authors:  Jignesh Lunagariya; Shenghui Zhong; Jianwei Chen; Defa Bai; Poonam Bhadja; Weili Long; Xiaojian Liao; Xiaoli Tang; Shihai Xu
Journal:  Mar Drugs       Date:  2016-09-03       Impact factor: 5.118

4.  Cytotoxicity Study of Cyclopentapeptide Analogues of Marine Natural Product Galaxamide towards Human Breast Cancer Cells.

Authors:  Jignesh Lunagariya; Xiaojian Liao; Weili Long; Shenghui Zhong; Poonam Bhadja; Hangbin Li; Bingxin Zhao; Shihai Xu
Journal:  Oxid Med Cell Longev       Date:  2017-12-19       Impact factor: 6.543

5.  Anthelmintic PF1022A: stepwise solid-phase synthesis of a cyclodepsipeptide containing N-methyl amino acids.

Authors:  Sebastian Lüttenberg; Frank Sondermann; Jürgen Scherkenbeck
Journal:  Tetrahedron       Date:  2011-12-16       Impact factor: 2.457

6.  Synthesis of Marine Cyclopeptide Galaxamide Analogues as Potential Anticancer Agents.

Authors:  Daichun Li; Xiaojian Liao; Shenghui Zhong; Bingxin Zhao; Shihai Xu
Journal:  Mar Drugs       Date:  2022-02-22       Impact factor: 5.118

  6 in total

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