BACKGROUND: Blood pressure (BP) is positively related to body mass index (BMI) in persons of both Caucasian and African origin, but the precise nature of the relationship is unclear. OBJECTIVE: To study the relationship between BP and BMI in a lean African population. DESIGN: A community-based cross-sectional study. METHODS: The BMI and BP were measured in 362 men and 592 women aged 40-75 years living in Ashanti, Ghana. In total, 498 lived in semi-urban areas and 456 in rural villages. RESULTS: The BMI was higher among semi-urban women [23.1 kg/m (95% confidence interval (CI), 22.5 to 23.6)] than semi-urban men [20.9 kg/m (95% CI, 20.6 to 21.5)], rural men [19.5 kg/m (95% CI, 19.1 to 19.9)] and rural women [19.9 kg/m (95% CI, 19.5 to 20.3)]. For systolic BP in women older than 52 years and in semi-urban women, the relationship was non-linear. The slope of the line below the change point ("knot") was greater than that above it. There was no evidence of non-linearity in men. For diastolic BP only younger women had a significant "knot" point at 18 kg/m. Again, the slope of the line below the "knot" was greater than that above it. In men, however, there was also evidence of a "knot" in younger and rural men, with the slope of the line below the "knot" being less that that above it (unlike in women). CONCLUSIONS: The relationship between BP and BMI is not linear, and is possibly sigmoid, but this may vary between subgroups.
BACKGROUND: Blood pressure (BP) is positively related to body mass index (BMI) in persons of both Caucasian and African origin, but the precise nature of the relationship is unclear. OBJECTIVE: To study the relationship between BP and BMI in a lean African population. DESIGN: A community-based cross-sectional study. METHODS: The BMI and BP were measured in 362 men and 592 women aged 40-75 years living in Ashanti, Ghana. In total, 498 lived in semi-urban areas and 456 in rural villages. RESULTS: The BMI was higher among semi-urban women [23.1 kg/m (95% confidence interval (CI), 22.5 to 23.6)] than semi-urban men [20.9 kg/m (95% CI, 20.6 to 21.5)], rural men [19.5 kg/m (95% CI, 19.1 to 19.9)] and rural women [19.9 kg/m (95% CI, 19.5 to 20.3)]. For systolic BP in women older than 52 years and in semi-urban women, the relationship was non-linear. The slope of the line below the change point ("knot") was greater than that above it. There was no evidence of non-linearity in men. For diastolic BP only younger women had a significant "knot" point at 18 kg/m. Again, the slope of the line below the "knot" was greater than that above it. In men, however, there was also evidence of a "knot" in younger and rural men, with the slope of the line below the "knot" being less that that above it (unlike in women). CONCLUSIONS: The relationship between BP and BMI is not linear, and is possibly sigmoid, but this may vary between subgroups.
Authors: Francesco P Cappuccio; Sally M Kerry; Adebowale Adeyemo; Amy Luke; Albert G B Amoah; Pascal Bovet; Myles D Connor; Terrence Forrester; Jean-Pierre Gervasoni; Gisela Kimbally Kaki; Jacob Plange-Rhule; Margaret Thorogood; Richard S Cooper Journal: Epidemiology Date: 2008-01 Impact factor: 4.822
Authors: Michèle Ramsay; Mayowa O Owolabi; Onoja M Akpa; Felix Made; Akinlolu Ojo; Bruce Ovbiagele; Dwomoa Adu; Ayesha A Motala; Bongani M Mayosi; Sally N Adebamowo; Mark E Engel; Bamidele Tayo; Charles Rotimi; Babatunde Salako; Rufus Akinyemi; Mulugeta Gebregziabher; Fred Sarfo; Kolawole Wahab; Godfred Agongo; Marianne Alberts; Stuart A Ali; Gershim Asiki; Romuald P Boua; F Xavier Gómez-Olivé; Felistas Mashinya; Lisa Micklesfield; Shukri F Mohamed; Engelbert A Nonterah; Shane A Norris; Hermann Sorgho; Stephen Tollman; Rulan S Parekh; Chishala Chishala; Kenneth Ekoru; Salina P Waddy; Emmanuel Peprah; George A Mensah; Ken Wiley; Jennifer Troyer Journal: Hypertension Date: 2020-03-16 Impact factor: 10.190
Authors: Jacob Plange-Rhule; Sally M Kerry; John B Eastwood; Frank B Micah; Sampson Antwi; Francesco P Cappuccio Journal: Int J Hypertens Date: 2018-04-05 Impact factor: 2.420
Authors: John B Eastwood; Sally M Kerry; Jacob Plange-Rhule; Frank B Micah; Sampson Antwi; Frances G Boa; Debasish Banerjee; Lynsey Emmett; Michelle A Miller; Francesco P Cappuccio Journal: Nephrol Dial Transplant Date: 2010-01-25 Impact factor: 5.992