| Literature DB >> 16092528 |
Abstract
Recent studies have shown that there is a pathway that is evolutionarily conserved for the insertion of proteins into the membrane in mitochondria, chloroplasts, and bacteria. In this pathway, the Oxa1/Alb3/YidC proteins are believed to function as membrane insertases that play an important role in the membrane protein biogenesis of respiratory and energy transduction proteins. Additional roles of the Oxa1/Alb3/YidC members may be in the lateral integration of proteins into the lipid bilayer, and in the folding and assembly of proteins into membrane protein complexes.Entities:
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Year: 2005 PMID： 16092528 DOI： 10.1080/09687860500041718
Source DB: PubMed Journal: Mol Membr Biol ISSN： 0968-7688 Impact factor: 2.857